{"id":7944,"date":"2017-01-26T16:32:28","date_gmt":"2017-01-26T23:32:28","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=7944"},"modified":"2023-03-03T09:57:59","modified_gmt":"2023-03-03T16:57:59","slug":"cu-spin-off-brings-science-to-the-medicine-of-exercise","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/cu-spin-off-brings-science-to-the-medicine-of-exercise\/","title":{"rendered":"CU spin-off brings science to the medicine of exercise"},"content":{"rendered":"
<\/div>

There\u2019s a low- to no-cost medicine that drastically improves the fortunes of patients. It\u2019s widely available without a prescription, but to many it\u2019s an unfamiliar pill. Some who try it find it bitter, and it has been known to trigger confusion and frustration. As commonly prescribed, it\u2019s hard to dose, and from a medication-compliance perspective, providers have a hard time tracking and monitoring it.<\/p>\n

We\u2019re talking about exercise. Maybe you\u2019ve heard it before: exercise is medicine<\/a>. Whether it\u2019s a muscle-ripping CrossFit routine or a walk around the park, exercise reduces risks across the health spectrum: heart <\/a>disease, diabetes<\/a>, injury, depression <\/a>and much more. But while the health care establishment has long employed scientific, structured approaches to understanding the benefits of exercise, it\u2019s lacked a good way of employing similar science and structure to help the vast numbers of patients who need the medicine of exercise. Thanks to a new method called Method, that\u2019s about to change for primary care patients at UCHealth and beyond.<\/p>\n

Nicholas Edwards, co-founder and chief scientific officer of CU-spinoff Method, is also director of Exercise-Medicine Integration in CU\u0092’s Department of Family Medicine, where the Method \u0096 already proven at CeDAR \u0096is poised for a big move into primary care at UCHealth.<\/figcaption><\/figure>\n

Method is a codified, computerized, app-enabled system that injects science and structure into exercise programming and planning by finding someone\u2019s unique metabolic fingerprint. It\u2019s the brainchild of Nicholas Edwards, MS, director of Exercise-Medicine Integration at the University of Colorado. Frank deGruy, MD<\/a>, who chairs CU\u2019s Department of Family Medicine, described Method as \u201cthe best thing I\u2019ve ever seen for implementing exercise into primary care.\u201d Family Medicine liked Edwards\u2019 method so much they helped launch Method and owns a stake in it \u2013 with a big assist from CU Innovations<\/a>.<\/p>\n

The Center for Dependency, Addiction, and Rehabilitation (CeDAR) at UCHealth University of Colorado Hospital is already an adherent. Edwards rolled out Method there in November 2014, focusing on college and pro athletes in CeDAR\u2019s Ascent Program. It\u2019s since expanded to every CeDAR residential treatment program patient \u2013 and far beyond. Edwards says Method is also in place at physical therapy, sports medicine, orthopedics and athletic training facilities in several states, with a half dozen additional facilities embracing the approach this month alone. All told, thousands of athletes and patients are using the system, he adds.<\/p>\n

Into the cells<\/strong><\/p>\n

Edwards, 32, knows a bit about exercise, both firsthand and as a student of it. He studied exercise science and dietetics at North Dakota State, where he played cornerback and also pole vaulted, clearing 16\u20192\u201d. His pugilist nose is a keepsake from his eight years as an amateur and professional mixed martial arts pro.<\/p>\n

Edwards in Brazilian jiu-jitsu mode in 2013, when he came in fifth at the World Jiu-Jitsu No Gi Championships.<\/figcaption><\/figure>\n

Edwards has worked on the University of Colorado Anschutz Medical Campus for years. As the Anschutz Health & Wellness Center\u2019s exercise testing coordinator, he devised the wellness assessment given to all incoming members. But Edwards also spent time working with professional and college athletes and sports teams and establishing fitness programs as well as entire sports medicine facilities. It was through a combination of that work and his CU experience that Method came about.<\/p>\n

The approach tailors exercise and strength programs to individuals based on what\u2019s happening in their bodies at the cellular level. It involves blood-based biomarker tests during exercise at increasing intensities. For an elite athlete, that may involve repeated sprints or doing deadlifts. For a couch potato, it might be standing up and sitting back down a few times from a chair.<\/p>\n

By pegging escalating heart rate to changes in blood markers, Method\u2019s approach establishes when someone transitions from aerobic to anaerobic (which happens when cells go from burning stored energy to burning what you just ate as fast-twitch muscles increasingly engage \u2013 and you breathe a lot harder) and then from anaerobic to catabolic (which happens when you max out and is ultimately counterproductive).<\/p>\n

With the relationship between heart rate and muscle-cell status in hand, a Method user can know exactly how the body\u2019s responding to exercise based on heart rate. The end result is faster return to play, healthier choices during exercise and lifestyle change, Edwards said.<\/p>\n

The elite first<\/strong><\/p>\n

That\u2019s a big step up from the old 220-minus-your-age approach of determining one\u2019s maximum heart rate and then estimating anaerobic and aerobic training zones based on standard formulas. Think about it, Edwards said: the exercise transition points of a 55-year-old former Olympic swimmer who\u2019s stayed in shape will look nothing like those of a sedentary obese diabetic of the same vintage. Their training programs should vastly different, too.<\/p>\n

Metabolic testing is not new \u2013 elite endurance athletes have been doing it for years. But metabolic testing has been absent from the gym, the rehab facility and the weight room, where the anaerobic exercise that builds strength as well as endurance reigns. It has left us to our own devices, which so often leads to ineffective workouts or injury. Method addresses this not only through the metabolic testing, but also via automated exercise programs and individual workouts that can adjust in real-time based on that metabolic testing.<\/p>\n

Adherents include two NFL and two NHL teams, including the Colorado Avalanche, for whom Edwards does sports science. Once a week during the season and more often during the preseason, Edwards is at practice or in the gym with the team, monitoring heart rates, oxygen, exercise readiness and intensities\u00a0 \u2013 and by extension, real-time work rates to make adjustments \u2013 of some of the world\u2019s top team sport athletes. If a player\u2019s not pushing quite hard enough for maximum gain, the coaches know; conversely, if someone\u2019s overdoing it, Edwards and coaches can ask the player to ease up.<\/p>\n

If CeDAR\u2019s experience with Method is any measure, it will be a hit in primary care. Method is now ingrained in CeDAR as a pillar of every residential patient\u2019s recovery program. Once medically cleared, they hit the gym for an hour a day, six mornings a week. Their Method smartphone apps carry tailored programs chosen from hundreds of exercises preloaded into Method or custom-added by Edwards or CeDAR exercise physiologist and nutrition consultant Casey Shivers. Many exercises have accompanying videos demonstrating proper technique. Shivers or Edwards are there to monitor groups of up to 20, answer questions, and offer guidance.<\/p>\n

Afterwards they can look at statistical reports Method creates. That data is later made anonymous and collected in a central database. Over time, Edwards and Family Medicine colleagues can use it to spot trends, such as what sorts of programs work best for certain types of patients, Edwards said.<\/p>\n

\u201cI truly believe this will change best practices over time, and right now, all the medical specialties using it are finding huge changes in people\u2019s lives,\u201d he said.<\/p>\n

Method works across the full spectrum of athleticism and fitness levels, Shivers said. Plus it gives patients a psychological boost. Progress in addiction recovery can be hard to measure when it comes to strengthening personal relationships or coping skills, she said, \u201cbut I can show somebody that they\u2019re different on a cellular level in 30 days.\u201d<\/p>\n

Patients can keep using Method at their own gyms after they leave CeDAR, she added, and when they do follow-on metabolic testing at 30 days, 60 days or even farther out, \u201cthe difference we see is kind of bananas.\u201d<\/p>\n

Beyond the body<\/strong><\/p>\n

Method brings other benefits, said LaTisha Bader, PhD, the CeDAR psychologist who leads the Ascent Program. It provides daily structure that addiction-recovery patients often lack. It also helps ensure that patients don\u2019t shift their addictive focus from substances to exercise, work out too hard and get hurt. It speeds up healing because clients feel stronger physically and are better positioned to do the spiritual and emotional heavy lifting so critical to their recovery.<\/p>\n

\u201cIt helps patients reconnect with this body that you\u2019ve numbed out and that you have used toxins to shut down,\u201d Bader said.<\/p>\n

deGruy and the CU Department of Family Medicine are betting that the same will hold for Family Medicine. He brought Edwards in as faculty in 2013 to address the general failure of U.S. primary care in prescribing exercise as medicine.<\/p>\n

\u201cWe have these cheesy, weak programs for exercise and they don\u2019t work. They\u2019re not very structured and they don\u2019t deal with the psychology or with health behavior change,\u201d deGruy said. \u201cI\u2019m a little bit embarrassed about how ineffective we are in prescribing exercise, and this goes right to the heart of that.\u201d<\/p>\n

Transferred tech<\/strong><\/p>\n

deGruy and David Clute, MBA<\/a>, the department\u2019s director of finance and administration, steered Edwards to CU\u2019s Anschutz Medical Campus technology transfer team, now known as CU Innovations<\/a>. Kimberly Muller, CU Innovations\u2019 director, said it\u2019s not the first time deGruy\u2019s organization knocked on the door.<\/p>\n

\u201cThe Department of Family Medicine takes a very proactive approach to innovation in trying to really help their faculty members take what they\u2019re doing and translate that for impact,\u201d Muller said.<\/p>\n

Edwards monitors the Colorado Avalanche during practice on Dec. 5. In a gym environment, Method\u0092’s group view can be sent to a big screen for group viewing. (Courtesy Nick Edwards)<\/figcaption><\/figure>\n

CU Innovations brought in Method\u2019s CEO, Craig Domeracki, helped establish trademarking and intellectual property protection, and set up the licensing and ownership structure for the company, Muller said.<\/p>\n

Now Edwards and the Department of Family Medicine are moving Method into primary care, the aim being to \u201cintegrate exercise deep into the fabric of somebody\u2019s personal care plan,\u201d Edwards said.<\/p>\n

\u201cThe goal is to get every patient involved \u2013 not only here, but to be a beacon for this across primary care and sports medicine around the U.S.,\u201d he added.<\/p>\n

UCHealth\u2019s A.F. Williams Family Medicine Clinic – Stapleton<\/a>, which is well familiar with pioneering change in primary care, is next up. deGruy is hoping to establish a partnership with CU\u2019s Physical Therapy program, which has space in the same Stapleton neighborhood building.<\/p>\n

\u201cWe\u2019ve got to be really careful about changing the workflow,\u201d he said. \u201cThose clinics run really tight.\u201d<\/p>\n

When used in a clinical setting, Method is covered by health insurers. That\u2019s important, deGruy said.<\/p>\n

\u201cWe\u2019re doing this because it\u2019s good patient care. But we can only do it if we don\u2019t lose too much money,\u201d he said.<\/p>\n

If Method is the right prescription for the medicine of exercise in primary care, others will follow, deGruy is convinced. At national family medicine gatherings, \u201cthey\u2019re going to want me in the front of the room talking about this.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

There\u2019s a low- to no-cost medicine that drastically improves the fortunes of patients. It\u2019s widely available without a prescription, but to many it\u2019s an unfamiliar pill. Some who try it find it bitter, and it has been known to trigger confusion and frustration. As commonly prescribed, it\u2019s hard to dose, and from a medication-compliance perspective, […]<\/p>\n","protected":false},"author":23,"featured_media":7950,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[5],"tags":[159,17,1129,207,773,271,1131,1128,1130,351,2148],"class_list":["post-7944","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovative-care","tag-addiction-and-rehabilitation","tag-addiction-treatment","tag-casey-shivers","tag-cedar","tag-colorado-avalanche","tag-exercise","tag-frank-degruy","tag-latisha-bader","tag-nicholas-edwards","tag-primary-care","tag-uchealth-center-for-dependency-addiction-and-rehabilitation"],"acf":[],"yoast_head":"\nCU spin-off brings science to the medicine of exercise - UCHealth Today<\/title>\n<meta name=\"description\" content=\"There\u2019s a low- to no-cost medicine that drastically improves the fortunes of patients. 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