{"id":70182,"date":"2023-06-05T14:20:49","date_gmt":"2023-06-05T20:20:49","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=70182"},"modified":"2026-04-02T15:15:23","modified_gmt":"2026-04-02T21:15:23","slug":"surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/","title":{"rendered":"Patient finds inner strength to survive triple threats of breast cancer, kidney disease and liver disease"},"content":{"rendered":"<div style=\"margin-top: 0px; margin-bottom: 0px;\" class=\"sharethis-inline-share-buttons\" ><\/div><figure id=\"attachment_70186\" aria-describedby=\"caption-attachment-70186\" style=\"width: 450px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-70186\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp\" alt=\"Jordyn, Jade, Karla and Carlos Jr. in a pumpkin-loving moment. Karla battled polycystic liver and kidney diseases + breast cancer. Photo courtesy of Karla Ojeda.\" width=\"450\" height=\"600\" \/><figcaption id=\"caption-attachment-70186\" class=\"wp-caption-text\">Karla Ojeda (second from right) had a kidney transplant that gave her a new lease on life. She is photographed with her children, Jordyn, Jade and Carlos Jr. in a pumpkin-loving moment. Photo courtesy of Karla Ojeda.<\/figcaption><\/figure>\n<p>The astrophysicist Neil deGrasse Tyson once said, \u201cThe Universe is under no obligation to make sense to you.\u201d He aimed his remark at those resistant to seeking answers in science. But they apply equally well to those whose lives are struck with seemingly random cruelty.<\/p>\n<p>Karla Ojeda is a 45-year-old wife, mother of three teenagers she calls her \u201cdriving force,\u201d and the proud daughter of strong immigrant parents. Her longtime job as Human Services Community Resources coordinator with Adams County satisfies her passion for helping people.<\/p>\n<p>Yet life has also mysteriously battered the strong moorings of Ojeda\u2019s life. A genetic mutation saddled her with <a id=\"\" href=\"https:\/\/www.kidney.org\/atoz\/content\/polycystic\" target=\"_blank\" rel=\"noopener\">polycystic kidney disease (PKD)<\/a>, an incurable condition that brought her kidneys to the brink of failure.<\/p>\n<p>Cysts also ravaged her liver, and Ojeda urgently required a transplant. In the midst of waiting for a donor liver, however, Ojeda was diagnosed with breast cancer. The assault left her wondering why such misfortune had been heaped upon her.<\/p>\n<p>\u201cI\u2019ve always believed that things happen for a reason,\u201d Ojeda says. \u201cSometimes you know why and sometimes you don\u2019t. Going through my medical journey, a lot of times, I didn\u2019t understand why things would happen, and I would get frustrated.\u201d<\/p>\n<p>Ojeda is still waiting for those answers. But through her own will and determination and skilled medical care at <a href=\"https:\/\/www.uchealth.org\/locations\/uchealth-university-of-colorado-hospital-uch\/\">UCHealth University of Colorado Hospital<\/a>, she has fought through the array of challenges and looks forward to a life free from the shackles of disease.<\/p>\n<h2><strong>Kidney disease makes its mark<\/strong><\/h2>\n<p>The major thread of Ojeda\u2019s health ordeal is PKD, a genetic condition that riddles the kidneys with fluid-filled cysts. Over time, the cysts grow and take over space from healthy tissue, greatly increasing the risk of kidney failure. Ojeda learned she had PKD during high school after a long, unexplained illness. At that point, she wasn\u2019t fazed by the diagnosis.<\/p>\n<figure id=\"attachment_70185\" aria-describedby=\"caption-attachment-70185\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-70185\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05140941\/PKD-and-Liver-Disease-Patient-2-Ojeda-Family-scaled.webp\" alt=\"Karla with her husband and children. From left: Carlos Jr., Jade, Karla, Carlos and Jordyn. Photo courtesy of Karla Ojeda.\" width=\"640\" height=\"427\" \/><figcaption id=\"caption-attachment-70185\" class=\"wp-caption-text\">Karla Ojeda with her husband and children. From left: Carlos Jr., Jade, Karla, Carlos and Jordyn. Photo courtesy of Karla Ojeda.<\/figcaption><\/figure>\n<p>\u201cI thought I was invincible,\u201d Ojeda said.<\/p>\n<p>She learned to control her blood pressure, limit her salt intake, drink plenty of water and exercise. She was particularly cautious during her three pregnancies. Her kidney function continued to worsen, but in 2018 she got some help from <a id=\"\" href=\"https:\/\/pkdcure.org\/tolvaptan\/\" target=\"_blank\" rel=\"noopener\">tolvaptan<\/a>, the first FDA-approved drug to treat PKD. The drug blocks the hormone vasopressin, which prevents an individual from urinating constantly, explained <a href=\"https:\/\/www.uchealth.org\/provider\/charles-edelstein-md-nephrology\/\">Dr. Charles Edelstein<\/a>, a kidney disease specialist who treats Ojeda in the <a href=\"https:\/\/www.uchealth.org\/locations\/uchealth-polycystic-kidney-disease-clinic-anschutz\/\">UCHealth Polycystic Kidney Disease Clinic \u2013 Anschutz Medical Campus<\/a>.<\/p>\n<p>\u201cVasopressin causes the cells lining the cysts in the kidneys to proliferate and the cysts to grow,\u201d Edelstein said. By blocking vasopressin, tolvaptan forces an individual to urinate frequently, thus slowing \u2013 but not stopping \u2013 cyst growth, he added.<\/p>\n<h2><strong>An unusual liver problem<\/strong><\/h2>\n<p>A more immediate problem for Ojeda, Edelstein added, was her polycystic liver disease (<a id=\"\" href=\"https:\/\/rarediseases.org\/rare-diseases\/polycystic-liver-disease\/\" target=\"_blank\" rel=\"noopener\">PLD<\/a>), which frequently accompanies PKD.<\/p>\n<p>\u201cMost patients have both [PKD and PLD],\u201d Edelstein said. \u201cNormally, the kidneys get big and cystic and fail, and the liver doesn\u2019t present a problem. For Karla, the case was the other way around. She needed a liver transplant before a kidney transplant, which is extremely unusual.\u201d<\/p>\n<p>The cysts in Ojeda\u2019s liver ballooned from a normal size of 2 pounds to 11. The organ wasn\u2019t failing, Edelstein said, but taking up so much space in the abdomen that other organs, like the intestines, couldn\u2019t function normally.<\/p>\n<p>\u201cI was very fatigued. Eating was hard,\u201d said Ojeda. \u201cI could feel the pressure in my abdomen, much like when I was pregnant.\u201d<\/p>\n<h2><strong>A surprise \u2013 and unwelcome \u2013 diagnosis, then a positive turn<\/strong><\/h2>\n<p>Ojeda was on the list for a liver transplant when she absorbed another unexpected blow. During a routine pre-transplant exam in May 2018, she received a mammogram that revealed she had breast cancer. The shocking diagnosis was magnified by the necessity to put the liver transplant on hold. It was a setback, but Ojeda said the <a href=\"https:\/\/www.uchealth.org\/locations\/uchealth-diane-o-connor-thompson-breast-center-anschutz\/\">breast cancer<\/a> and <a href=\"https:\/\/www.uchealth.org\/locations\/uchealth-transplant-services-anschutz\/\">transplant<\/a> teams at UCH worked together to restore her health and keep the search for an organ donor on track.<\/p>\n<p>After a lumpectomy to remove the cancerous tumor, Ojeda underwent eight rounds of weekly radiation treatments. Five years later, she is cancer-free.<\/p>\n<p>\u201cI never felt hopeless at all,\u201d she said. She acknowledges, however, the period of treatment and waiting for a liver took both a physical and emotional toll.<\/p>\n<figure id=\"attachment_70188\" aria-describedby=\"caption-attachment-70188\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-70188\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141455\/karla5eee.webp\" alt=\"Kidney specialist Dr. Charles Edelstein cared for Karla through the UCHealth Polycystic Kidney Disease Clinic. Photo by the CU School of Medicine.\" width=\"300\" height=\"375\" \/><figcaption id=\"caption-attachment-70188\" class=\"wp-caption-text\">Kidney specialist Dr. Charles Edelstein cared for Karla through the UCHealth Polycystic Kidney Disease Clinic. Photo by the CU School of Medicine.<\/figcaption><\/figure>\n<p>\u201cThere was a lot I had to give up,\u201d Ojeda said. \u201cI couldn\u2019t always go to my kids\u2019 activities or be in public because of my fatigue and side effects from the radiation.\u201d<\/p>\n<p>She considered taking time off from work but decided against it.<\/p>\n<p>\u201cI felt that work was the only thing that remained normal,\u201d she said, crediting her employer for giving her accommodations through the difficult time.<\/p>\n<p>\u201cWork helped to keep me grounded,\u201d Ojeda said. \u201cIt was one of the few things I had a little bit of control over.\u201d<\/p>\n<p>She also turned back her life-threatening liver disease in January 2019, when UCHealth transplant specialist <a href=\"https:\/\/www.uchealth.org\/provider\/james-pomposelli\/\">Dr. James Pomposelli<\/a> transplanted her new liver successfully.<\/p>\n<p>\u201cIn about six to eight weeks, I felt better, and now it feels fantastic,\u201d Ojeda said.<\/p>\n<h2><strong>Battle with kidney disease continues<\/strong><\/h2>\n<p>Throughout her struggles with PLD and breast cancer, however, her cyst-ridden kidneys continued to deteriorate. They grew from the normal size of a fist to the girth of a football, and their function decreased. Ojeda felt more fatigued, and her blood pressure increased, along with bouts of headaches and lightheadedness.<\/p>\n<p>\u201cI had very little appetite, and I was exhausted after eight hours of sleep,\u201d she said. While the tolvaptan helped to slow the progression of her PKD, she also had to get up frequently to urinate, which contributed to her exhaustion.<\/p>\n<p>Edelstein eventually warned her that she would soon need dialysis to support her failing kidneys. Ojeda asked for a bit more time to see if the transplant team could find a donor. A living donor was not a match, but a paired donation \u2013 which involves swapping living donor kidneys with compatible recipients \u2013 provided a solution. <a href=\"https:\/\/www.uchealth.org\/provider\/thomas-pshak-md\/\">Dr. Thomas Pshak<\/a> successfully performed Ojeda\u2019s kidney transplant in March 2022.<\/p>\n<p>\u201cThe kidney works beautifully,\u201d Ojeda said. She estimated that she is back to 90% of how she was before the \u201cemotional rollercoaster\u201d of health problems.<\/p>\n<h2><strong>A national leader in PKD treatment and research<\/strong><\/h2>\n<p>Her success story has many supports. The Polycystic Kidney Disease Clinic, staffed by Edelstein, fellow kidney disease specialist <a href=\"https:\/\/www.uchealth.org\/provider\/michel-chonchol-md-nephrology\/\">Dr. Michel Chonchol<\/a> and nurse Amy Wilbur, is a <a id=\"\" href=\"https:\/\/pkdcure.org\/carecenters\/\" target=\"_blank\" rel=\"noopener\">PKD Foundation Center of Excellence<\/a>\u00a0based on its expertise, integrated care, research, and network of providers. One concrete benefit of that status for Karla Ojeda and other PKD patients: the PKD Clinic is housed on the same floor as the Transplant Clinic, and the providers in each work closely together. Edelstein and Pshak manage Ojeda\u2019s kidney care, while Pomposelli and liver transplant specialist <a href=\"https:\/\/www.uchealth.org\/provider\/james-burton-md-transplant-hepatology\/\">Dr. James Burton<\/a> coordinate her liver care.<\/p>\n<p>Edelstein also noted that the University of Colorado School of Medicine has a long history of expertise and leadership in PKD clinical care and research. It began with <a href=\"https:\/\/www.nationalacademies.org\/news\/2019\/09\/patricia-gabow-receives-lienhard-award-from-national-academy-of-medicine-for-transforming-safety-net-hospital-into-nationally-recognized-health-system\">Dr. Patricia Gabow<\/a> in the 1970s and continued with the late <a href=\"https:\/\/journals.lww.com\/jasn\/pages\/articleviewer.aspx?year=2021&amp;issue=05000&amp;article=00005&amp;type=Fulltext\">Dr. Robert Schrier<\/a>, who brought the school\u2019s <a id=\"\" href=\"https:\/\/medschool.cuanschutz.edu\/renal\" target=\"_blank\" rel=\"noopener\">Division of Renal Diseases and Hypertension<\/a> to national prominence during two decades of leadership.<\/p>\n<p>\u201cIt\u2019s led to many patients coming to our clinic from out of state,\u201d Edelstein. The reach stretches across the Rocky Mountain region and as far away as Alaska, he added.<\/p>\n<p>Ojeda, who lives in Henderson, didn\u2019t have to travel nearly that far to reach the clinic, and she is grateful to have had it as a resource. \u201cDr. Edelstein was amazing,\u201d Ojeda said. \u201cHe takes the time to really get to know his patients.\u201d<\/p>\n<h2><strong>Specialty care and family ease mental health burdens<\/strong><\/h2>\n<p>Ojeda said she also appreciated the \u201cwell-rounded care\u201d that UCHealth offered. For example, she faced mental health challenges after the transplants, partly because of a loss of self-esteem she attributes to weight gain caused by the prednisone she takes as a post-transplant immunosuppressant. She also suffered feelings of guilt for putting her family through her ordeal. Ojeda said <a href=\"https:\/\/www.uchealth.org\/provider\/melissa-kwitowski-phd\/\">Dr. Melissa Kwitowski<\/a> with the <a id=\"\" href=\"https:\/\/medschool.cuanschutz.edu\/psychiatry\" target=\"_blank\" rel=\"noopener\">CU Department of Psychiatry<\/a> helped her deal constructively with these painful thoughts.<\/p>\n<p>\u201cI\u2019m working back, and things are falling into place,\u201d Ojeda said.<\/p>\n<p>She credits her husband for being instrumental in helping her to maintain her strength and resolve during difficult times, but she has a fortress of support. For example, her parents, immigrants from Chile, instilled a strong ethic of personal growth and commitment, she said.<\/p>\n<p>\u201cMy parents emphasized the importance of getting a good education and working hard to go far in life and be able to enjoy it,\u201d Ojeda said. She added that her dad, in particular, prodded her to stay positive as she battled through her cancer treatments and transplant surgeries.<\/p>\n<p>An extended group of people, including her sisters-in-law, whom she calls \u201cmy pillars,\u201d also assisted Ojeda through hard times, helping her husband, watching the kids and simply keeping her company.<\/p>\n<p>Most of all, the three kids, Jade, Carlos and Jordyn, pushed her to battle back.<\/p>\n<p>\u201cI kept telling myself that I have to keep going,\u201d she said. \u201cI want to see them grow up, graduate from high school and do whatever they want to do with their lives. I always kept that in the back of my head.\u201d<\/p>\n<h2><strong>A new well of strength discovered<\/strong><\/h2>\n<p>The long periods of missing their activities are behind Ojeda. She experienced the \u201cindescribable joy\u201d of watching oldest daughter Jade\u2019s high school graduation on May 22 and has enjoyed watching all the kids play basketball, soccer, and volleyball and participate in choir.<\/p>\n<p>The Universe hasn\u2019t explained itself to Ojeda. She doesn\u2019t claim to understand why she has borne the toll of disease. But she has learned from her experience.<\/p>\n<p>\u201cI concluded that people can go through really hard things and have a beautiful, positive ending,\u201d Ojeda said. \u201cWhen you are struggling and going through it, it\u2019s hard to see the light at the end of the tunnel. But as long as you believe in yourself and have a good support system and people who love you, you can make it through just about anything in life. A lot of times, I thought, \u2018I can\u2019t do this.\u2019 I learned that I could.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The astrophysicist Neil deGrasse Tyson once said, \u201cThe Universe is under no obligation to make sense to you.\u201d He aimed his remark at those resistant to seeking answers in science. But they apply equally well to those whose lives are struck with seemingly random cruelty. Karla Ojeda is a 45-year-old wife, mother of three teenagers [&hellip;]<\/p>\n","protected":false},"author":2143,"featured_media":70186,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[5],"tags":[655,6835,28,3414,3230,4502,39],"class_list":["post-70182","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovative-care","tag-breast-cancer","tag-breast-cancer-treatment","tag-cancer-care-oncology","tag-kidney-transplants","tag-liver-transplants","tag-paired-organ-donation","tag-transplant-services"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Surviving triple threats: polycystic liver and kidney diseases + breast cancer - UCHealth Today<\/title>\n<meta name=\"description\" content=\"Karla Ojeda survived breast cancer and then two transplants that solved life-threatening polycystic liver disease and kidney disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Patient finds inner strength to survive triple threats of breast cancer, kidney disease and liver disease\" \/>\n<meta property=\"og:description\" content=\"Karla Ojeda survived breast cancer and then two transplants that solved life-threatening polycystic liver disease and kidney disease.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"UCHealth Today\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/uchealthorg\/\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-05T20:20:49+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-02T21:15:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.jpeg\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Tyler Smith\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@uchealth\" \/>\n<meta name=\"twitter:site\" content=\"@uchealth\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Tyler Smith\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"9 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/\"},\"author\":{\"name\":\"Tyler Smith\",\"@id\":\"https:\/\/www.uchealth.org\/today\/#\/schema\/person\/98c85c0e40c4933eedcec2cd054f349d\"},\"headline\":\"Patient finds inner strength to survive triple threats of breast cancer, kidney disease and liver disease\",\"datePublished\":\"2023-06-05T20:20:49+00:00\",\"dateModified\":\"2026-04-02T21:15:23+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/\"},\"wordCount\":1821,\"publisher\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp\",\"keywords\":[\"Breast cancer\",\"Breast cancer treatment\",\"Cancer care\",\"Kidney transplants\",\"Liver transplants\",\"Paired organ donation\",\"Transplant services\"],\"articleSection\":[\"Innovative care\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/\",\"url\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/\",\"name\":\"Surviving triple threats: polycystic liver and kidney diseases + breast cancer - UCHealth Today\",\"isPartOf\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp\",\"datePublished\":\"2023-06-05T20:20:49+00:00\",\"dateModified\":\"2026-04-02T21:15:23+00:00\",\"description\":\"Karla Ojeda survived breast cancer and then two transplants that solved life-threatening polycystic liver disease and kidney disease.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#primaryimage\",\"url\":\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp\",\"contentUrl\":\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp\",\"width\":1200,\"height\":1600,\"caption\":\"Jordyn, Jade, Karla and Carlos Jr. in a pumpkin-loving moment. Karla battled polycystic liver and kidney diseases + breast cancer. Photo courtesy of Karla Ojeda.\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.uchealth.org\/today\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Patient finds inner strength to survive triple threats of breast cancer, kidney disease and liver disease\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.uchealth.org\/today\/#website\",\"url\":\"https:\/\/www.uchealth.org\/today\/\",\"name\":\"UCHealth Today\",\"description\":\"UCHealth Today\",\"publisher\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.uchealth.org\/today\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.uchealth.org\/today\/#organization\",\"name\":\"UCHealth\",\"url\":\"https:\/\/www.uchealth.org\/today\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.uchealth.org\/today\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/04\/24135149\/UCHealth-square-logo-1000x1000-1.jpg\",\"contentUrl\":\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/04\/24135149\/UCHealth-square-logo-1000x1000-1.jpg\",\"width\":1000,\"height\":1000,\"caption\":\"UCHealth\"},\"image\":{\"@id\":\"https:\/\/www.uchealth.org\/today\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/uchealthorg\/\",\"https:\/\/x.com\/uchealth\",\"https:\/\/www.instagram.com\/uchealth\/\",\"https:\/\/www.linkedin.com\/school\/14839\/\",\"https:\/\/www.pinterest.com\/uchealthorg\/\",\"https:\/\/www.youtube.com\/channel\/UC41SJI79yjZIe96OajzN22g\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.uchealth.org\/today\/#\/schema\/person\/98c85c0e40c4933eedcec2cd054f349d\",\"name\":\"Tyler Smith\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/secure.gravatar.com\/avatar\/d9cf06f094860ff4c88dfe85d3c79a05724744cb3f865253e7b928d904aaad8e?s=96&d=mm&r=g\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/d9cf06f094860ff4c88dfe85d3c79a05724744cb3f865253e7b928d904aaad8e?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/d9cf06f094860ff4c88dfe85d3c79a05724744cb3f865253e7b928d904aaad8e?s=96&d=mm&r=g\",\"caption\":\"Tyler Smith\"},\"description\":\"Tyler Smith has been a health care writer, with a focus on hospitals, since 1996. He served as a writer and editor for the Marketing and Communications team at University of Colorado Hospital and UCHealth from 2007 to 2017. More recently, he has reported for and contributed stories to the University of Colorado School of Medicine, the Colorado School of Public Health and the Colorado Bioscience Association.\",\"url\":\"https:\/\/www.uchealth.org\/today\/author\/smiths3\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Surviving triple threats: polycystic liver and kidney diseases + breast cancer - UCHealth Today","description":"Karla Ojeda survived breast cancer and then two transplants that solved life-threatening polycystic liver disease and kidney disease.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/","og_locale":"en_US","og_type":"article","og_title":"Patient finds inner strength to survive triple threats of breast cancer, kidney disease and liver disease","og_description":"Karla Ojeda survived breast cancer and then two transplants that solved life-threatening polycystic liver disease and kidney disease.","og_url":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/","og_site_name":"UCHealth Today","article_publisher":"https:\/\/www.facebook.com\/uchealthorg\/","article_published_time":"2023-06-05T20:20:49+00:00","article_modified_time":"2026-04-02T21:15:23+00:00","og_image":[{"url":"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.jpeg","type":"image\/jpeg"}],"author":"Tyler Smith","twitter_card":"summary_large_image","twitter_creator":"@uchealth","twitter_site":"@uchealth","twitter_misc":{"Written by":"Tyler Smith","Est. reading time":"9 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#article","isPartOf":{"@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/"},"author":{"name":"Tyler Smith","@id":"https:\/\/www.uchealth.org\/today\/#\/schema\/person\/98c85c0e40c4933eedcec2cd054f349d"},"headline":"Patient finds inner strength to survive triple threats of breast cancer, kidney disease and liver disease","datePublished":"2023-06-05T20:20:49+00:00","dateModified":"2026-04-02T21:15:23+00:00","mainEntityOfPage":{"@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/"},"wordCount":1821,"publisher":{"@id":"https:\/\/www.uchealth.org\/today\/#organization"},"image":{"@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp","keywords":["Breast cancer","Breast cancer treatment","Cancer care","Kidney transplants","Liver transplants","Paired organ donation","Transplant services"],"articleSection":["Innovative care"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/","url":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/","name":"Surviving triple threats: polycystic liver and kidney diseases + breast cancer - UCHealth Today","isPartOf":{"@id":"https:\/\/www.uchealth.org\/today\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#primaryimage"},"image":{"@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp","datePublished":"2023-06-05T20:20:49+00:00","dateModified":"2026-04-02T21:15:23+00:00","description":"Karla Ojeda survived breast cancer and then two transplants that solved life-threatening polycystic liver disease and kidney disease.","breadcrumb":{"@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#primaryimage","url":"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp","contentUrl":"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/06\/05141047\/PKD-and-Liver-Disease-Patient-3-Karla-and-Kids-scaled.webp","width":1200,"height":1600,"caption":"Jordyn, Jade, Karla and Carlos Jr. in a pumpkin-loving moment. Karla battled polycystic liver and kidney diseases + breast cancer. Photo courtesy of Karla Ojeda."},{"@type":"BreadcrumbList","@id":"https:\/\/www.uchealth.org\/today\/surviving-triple-threats-polycystic-liver-and-kidney-diseases-and-breast-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.uchealth.org\/today\/"},{"@type":"ListItem","position":2,"name":"Patient finds inner strength to survive triple threats of breast cancer, kidney disease and liver disease"}]},{"@type":"WebSite","@id":"https:\/\/www.uchealth.org\/today\/#website","url":"https:\/\/www.uchealth.org\/today\/","name":"UCHealth Today","description":"UCHealth Today","publisher":{"@id":"https:\/\/www.uchealth.org\/today\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.uchealth.org\/today\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.uchealth.org\/today\/#organization","name":"UCHealth","url":"https:\/\/www.uchealth.org\/today\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.uchealth.org\/today\/#\/schema\/logo\/image\/","url":"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/04\/24135149\/UCHealth-square-logo-1000x1000-1.jpg","contentUrl":"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2020\/04\/24135149\/UCHealth-square-logo-1000x1000-1.jpg","width":1000,"height":1000,"caption":"UCHealth"},"image":{"@id":"https:\/\/www.uchealth.org\/today\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/uchealthorg\/","https:\/\/x.com\/uchealth","https:\/\/www.instagram.com\/uchealth\/","https:\/\/www.linkedin.com\/school\/14839\/","https:\/\/www.pinterest.com\/uchealthorg\/","https:\/\/www.youtube.com\/channel\/UC41SJI79yjZIe96OajzN22g"]},{"@type":"Person","@id":"https:\/\/www.uchealth.org\/today\/#\/schema\/person\/98c85c0e40c4933eedcec2cd054f349d","name":"Tyler Smith","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/d9cf06f094860ff4c88dfe85d3c79a05724744cb3f865253e7b928d904aaad8e?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/d9cf06f094860ff4c88dfe85d3c79a05724744cb3f865253e7b928d904aaad8e?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/d9cf06f094860ff4c88dfe85d3c79a05724744cb3f865253e7b928d904aaad8e?s=96&d=mm&r=g","caption":"Tyler Smith"},"description":"Tyler Smith has been a health care writer, with a focus on hospitals, since 1996. He served as a writer and editor for the Marketing and Communications team at University of Colorado Hospital and UCHealth from 2007 to 2017. More recently, he has reported for and contributed stories to the University of Colorado School of Medicine, the Colorado School of Public Health and the Colorado Bioscience Association.","url":"https:\/\/www.uchealth.org\/today\/author\/smiths3\/"}]}},"coauthors":[{"id":2143,"name":"Tyler Smith","link":"https:\/\/www.uchealth.org\/today\/author\/smiths3\/"}],"_links":{"self":[{"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/posts\/70182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/users\/2143"}],"replies":[{"embeddable":true,"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/comments?post=70182"}],"version-history":[{"count":10,"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/posts\/70182\/revisions"}],"predecessor-version":[{"id":70453,"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/posts\/70182\/revisions\/70453"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/media\/70186"}],"wp:attachment":[{"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/media?parent=70182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/categories?post=70182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.uchealth.org\/today\/wp-json\/wp\/v2\/tags?post=70182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}