{"id":69981,"date":"2023-05-11T14:29:31","date_gmt":"2023-05-11T20:29:31","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=69981"},"modified":"2025-01-15T09:36:17","modified_gmt":"2025-01-15T16:36:17","slug":"rare-infection-of-aortic-endograft-sets-life-saving-surgery-in-motion","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/rare-infection-of-aortic-endograft-sets-life-saving-surgery-in-motion\/","title":{"rendered":"Rare infection of aortic endograft sets life-saving surgery in motion"},"content":{"rendered":"<div style=\"margin-top: 0px; margin-bottom: 0px;\" class=\"sharethis-inline-share-buttons\" ><\/div><figure id=\"attachment_69984\" aria-describedby=\"caption-attachment-69984\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-69984\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/05\/11141731\/JackDebbieSargent_portrait.webp\" alt=\"Jack and Debbie Sargent. Photo for UCHealth by Cyrus McCrimmon.\" width=\"640\" height=\"491\" \/><figcaption id=\"caption-attachment-69984\" class=\"wp-caption-text\">Jack and Debbie Sargent at their home in Denver.\u00a0 Jack had a complex surgery to replace his abdominal aorta. Photos by Cyrus McCrimmon, for UCHealth.<\/figcaption><\/figure>\n<p>So often, the fix of the fix is a lot trickier than the original fix. That was certainly the case with Jack Sargent.<\/p>\n<p>Sargent was 73 and enjoying an active retirement of golfing and spending time with wife, Debbie, when routine scans at a local hospital found an abdominal aortic aneurysm in 2016. AAAs, as they\u2019re known, involve a ballooning of the major artery that runs down from the heart and between the kidneys before branching off at about the belly button into the iliac arteries that supply the legs. AAAs often have no symptoms until they burst, at which point you have a roughly two-in-10 chance of even surviving long enough to make it to a hospital.<\/p>\n<p>The predominant <a href=\"https:\/\/www.uchealth.org\/diseases-conditions\/vascular-disease-care\/\">AAA treatment<\/a> involves inserting a wire-mesh-fortified plastic sleeve (called an endograft) into the ballooning section of aorta. It\u2019s done using a catheter inserted into one of those iliac arteries near the groin. The procedure is called an endovascular aneurism repair, or <a id=\"\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6658877\/\" target=\"_blank\" rel=\"noopener\">EVAR<\/a>. Blood then flows through the graft, taking pressure off the distended aorta.<\/p>\n<p>Sargent had an endograft inserted, and for three years, he golfed and spent time with Debbie as before. But on July 2, 2019, while prepping a neighborhood Fourth of July picnic and parade he had made a habit of organizing, Sargent fell ill. Debbie found him collapsed on the floor of the master bathroom, delirious. Paramedics measured his blood pressure at about half of what it should have been and his fever at 105 degrees. They rushed him to <a href=\"https:\/\/www.uchealth.org\/locations\/uchealth-university-of-colorado-hospital-uch\/\">UCHealth University of Colorado Hospital<\/a> on the <a href=\"https:\/\/www.uchealth.org\/locations\/uchealth-at-university-of-colorado-anschutz-medical-campus\/\">Anschutz Medical Campus<\/a>.<\/p>\n<h2><strong>The right place for heart care<\/strong><\/h2>\n<p>University of Colorado School of Medicine Vascular Surgeon <a href=\"https:\/\/www.uchealth.org\/provider\/max-wohlauer-md\/\">Dr. Max Wohlauer<\/a> was on call at UCH that day. A CT scan and blood and other tests confirmed his suspicion that Sargent\u2019s graft had become infected \u2013 a rarity that occurs perhaps once every 1,000 EVAR procedures \u2013 and that the infection had reached the bloodstream. That\u2019s sepsis, and it\u2019s a mortal threat.<\/p>\n<p>Over the next few days, the UCHealth team\u2019s goal was to get Sargent\u2019s sepsis under control to the point that surgery was possible. CU School of Medicine infectious disease specialist <a id=\"\" href=\"https:\/\/www.uchealth.org\/provider\/molly-eaton-md\/\" target=\"_blank\" rel=\"noopener\">Dr. Molly Eaton<\/a> established the culprit to be <a id=\"\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK553032\/\" target=\"_blank\" rel=\"noopener\"><em>Bacteroides fragilis<\/em><\/a>, an anaerobic bug that\u2019s common in the lower gastrointestinal tract.<\/p>\n<figure id=\"attachment_69986\" aria-describedby=\"caption-attachment-69986\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-69986\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/05\/11142007\/Jack-Sargent-portrait.webp\" alt=\"A rare infection led to Jack Sargent\u2019s complex vascular surgery. Photo for UCHealth by Cyrus McCrimmon.\" width=\"640\" height=\"423\" \/><figcaption id=\"caption-attachment-69986\" class=\"wp-caption-text\">Jack Sargent after surgery to replace his abdominal aorta. Photo by Cyrus McCrimmon, for UCHealth.<\/figcaption><\/figure>\n<p>Antibiotics helped, but the source of the infection had to go. If not, Wohlauer said, \u201cEventually, the aorta gets infected and ruptures, especially with something like <em>Bacteroides<\/em>, so he was at risk of dying from an aneurysm rupture or from sepsis.\u201d<\/p>\n<p>While EVAR-related infections are rare, UCH is an aortic referral center, and doctors there probably treat more of them than any other hospital in the region, Wohlauer says. Such care takes a multidisciplinary team. The one treating Sargent included the vascular surgery team, including Wohlauer, Eaton and other infectious-disease specialists, surgical intensivists, critical-care specialists, hospital medicine physicians, gastroenterologists \u2013 not to mention nurses, medical technicians, case managers, respiratory therapists, and nutritionists.<\/p>\n<h2><strong>Replacing a section of aorta<\/strong><\/h2>\n<p>On July 12, Wohlauer operated on Sargent, cleaning out the badly infected endograft and surrounding tissue and replacing a four-inch section of aorta with that of a cadaveric donor. The surgery took up a good portion of the day. When it was over, Dr. Wohlauer came out to the waiting room where Debbie, their son Aaron Sargent, and Debbie\u2019s sister had been waiting.<\/p>\n<p>\u201cWould you like to see Jack?\u201d he asked.<\/p>\n<p>The family followed the surgeon to the ICU, where various lines and a respirator kept him alive. He was bloated, and his blood pressure was still low. Debbie was prepared to spend yet another night in the hospital, but the nurses suggested she go home and get some rest.<\/p>\n<p>\u201cOne of us will be with him all night,\u201d one told her. \u201cJack\u2019s going to need you in the morning.\u201d<\/p>\n<figure id=\"attachment_69988\" aria-describedby=\"caption-attachment-69988\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-69988\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/05\/11142227\/Jack-Debbie-Sargent-golf-course.webp\" alt=\"Jack and Debbie out for a walk on the golf course near their home. Photo for UCHealth by Cyrus McCrimmon.\" width=\"640\" height=\"435\" \/><figcaption id=\"caption-attachment-69988\" class=\"wp-caption-text\">Jack and Debbie Sargent near their home. Photo by Cyrus McCrimmon, for UCHealth.<\/figcaption><\/figure>\n<p>Four days later, Jack moved to a step-down unit. There, over the next few days, Debbie and Aaron \u2013 an emergency medical technician \u2013 proved so adept at keeping his stapled surgical incision clean that the UCHealth team felt comfortable discharging him a few days later, on July 22. Back home, he could sit on the patio and watch the golfers on the green behind their house.<\/p>\n<p>He and Debbie came back to UCH daily for several weeks. Sargent received antibiotic infusions to make sure the infection didn\u2019t return. He was still in a wheelchair for the first couple of weeks. When came in using a walker one day, \u201cEverybody in there started clapping and cheering,\u201d Debbie said.<\/p>\n<h2><strong>Paying it forward in thanks for their care<\/strong><\/h2>\n<p>On the one-year anniversary of the surgery, Debbie had photos taken of her and her husband out in the backyard with the golf course in the background. They framed one and gave it to Wohlauer, who displayed it in his office.<\/p>\n<p>Since Jack\u2019s recovery, the Sargents have added volunteering at Childrens Hospital Colorado on the Anschutz Medical Campus to their slate of activities. They spend hours in the surgery waiting area each Tuesday and Thursday. It\u2019s their way of paying forward their care at UCHealth, Sargent says.<\/p>\n<figure id=\"attachment_69990\" aria-describedby=\"caption-attachment-69990\" style=\"width: 400px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-69990\" src=\"https:\/\/uchealth-wp-uploads.s3.amazonaws.com\/wp-content\/uploads\/sites\/6\/2023\/05\/11142454\/UCHealth_JackDebbieSargent28.webp\" alt=\"Jack and Debbie Sargent with Dr. Max Wohlauer. Photo courtesy of Jack and Debbie Sargent.\" width=\"400\" height=\"419\" \/><figcaption id=\"caption-attachment-69990\" class=\"wp-caption-text\">Jack and Debbie Sargent with Dr. Max Wohlauer. Photo courtesy of Jack and Debbie Sargent.<\/figcaption><\/figure>\n<p>\u201cThat hospital is incredible, and those people, they save lives every day,\u201d he said. \u201cIt was just wonderful, and even sitting here talking about it and remembering some of the things they did \u2013 I kind of get emotional about it.\u201d<\/p>\n<p>Debbie says she was writing down the names of those she would one day like to thank \u2013 from housekeeping staff to nurses to medical residents to medical techs to physicians \u2013 until there were so many, she lost track.<\/p>\n<p>\u201cI would love to thank all these people,\u201d she said. \u201cThe teamwork and the camaraderie and the skillsets they have \u2013 they\u2019re all, in my mind, miracle workers.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>So often, the fix of the fix is a lot trickier than the original fix. That was certainly the case with Jack Sargent. Sargent was 73 and enjoying an active retirement of golfing and spending time with wife, Debbie, when routine scans at a local hospital found an abdominal aortic aneurysm in 2016. AAAs, as [&hellip;]<\/p>\n","protected":false},"author":23,"featured_media":69984,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[7],"tags":[9184,3512],"class_list":["post-69981","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-stories","tag-cardiac-rehab","tag-heart-and-vascular-care-cardiovascular"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Infection of aortic endograft sets life-saving surgery in motion - 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