{"id":4685,"date":"2016-07-21T00:00:00","date_gmt":"2016-07-21T06:00:00","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/2016\/07\/21\/trial-aims-to-help-patients-zap-migraines\/"},"modified":"2021-07-09T12:03:22","modified_gmt":"2021-07-09T18:03:22","slug":"trial-aims-to-help-patients-zap-migraines","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/trial-aims-to-help-patients-zap-migraines\/","title":{"rendered":"Trial aims to help patients zap migraines"},"content":{"rendered":"
<\/div>
<\/h5>\n

Shauna Stansbury\u2019s 14th birthday party was memorable, but not for the right reasons.<\/p>\n

The celebration turned sour when Stansbury, now 21, was beset by a headache she compared to \u201csomeone hammering my skull from the inside, a constant pounding.\u201d The pain reduced her to tears, she recalled.<\/p>\n

The birthday gone bad began a long ordeal for Stansbury, who said she experienced headaches of varying intensity nearly every day for the next seven years. They frequently progressed to what she described as migraines that sent her to dark rooms where she pressed cool cloths to her forehead to stave off nausea and vomiting.<\/p>\n

\"Shauna
Shauna Stansbury says the Cefaly device has helped to relieve the chronic headaches that have plagued her for seven years.<\/figcaption><\/figure>\n

The bouts forced her to get home schooling and prevented her from working. After her family moved from Westcliffe, Colo., to Denver, she enrolled at Front Range Community College, but the headaches led her to quit after one semester.<\/p>\n

\u201cHaving headaches all the time was a killer,\u201d Stansbury said. \u201cThey had a crippling effect. I couldn\u2019t think or focus.\u201d<\/p>\n

The headaches haven\u2019t gone away completely, but they are now a smaller part of her life, thanks to a device called the Cefaly<\/a> that she received as part of a clinical trial led by Marius Birlea, MD<\/a>, a neurologist with the University of Colorado School of Medicine. Birlea directs the Headache Clinic<\/a> at University of Colorado Hospital.<\/p>\n

Pounding on migraines<\/strong><\/p>\n

The Cefaly was approved by the FDA as the first migraine-prevention device in 2014. It fits across the forehead like a headband. An electrode delivers electrical stimulation to the upper branches of the trigeminal nerve, which is responsible for transmitting feeling from the face to the brain. The trigeminal nerve plays a major role in the brain-activity disturbances that trigger migraines<\/a>.<\/p>\n

The original randomized, controlled Cefaly trial targeted 67 patients with \u201cepisodic\u201d migraines \u2013 six or seven days a month on average, Birlea said. The trial showed the device to be safe and effective in reducing the number of headaches patients experienced and the number of medications they took to control them. Birlea said the Cefaly seems to work in some patients by electrically stimulating pathways in the brain that suppress pain and restoring its capacity to defend against migraine.<\/p>\n

Birlea\u2019s trial<\/a> sets its sights on determining if the Cefaly can help prevent headaches in chronic migraine sufferers like Stansbury who have 15 or more headache days per month and have not been able to control them consistently with prescribed medications.<\/p>\n

\u201cThese are very disabled patients,\u201d Birlea said. \u201cMany of them can\u2019t go to work and can\u2019t advance socially because of their headaches.\u201d<\/p>\n

The headache diaries<\/strong><\/p>\n

\"Marius
Marius Birlea, MD, medical director of the Headache Clinic at UCH, leads a trial that tests the effectiveness of the Cefaly in treating patients with chronic headaches, including migraines.<\/figcaption><\/figure>\n

His trial is still enrolling patients, but as of late June, 31 \u2013 including Stansbury \u2013 had completed the trial\u2019s regimen. Patients record in a paper diary the number of headaches they experienced, their intensity and medications they took. After a one-month baseline period, they use the Cefaly for at least one 20-minute period each day and record the same information for three months.<\/p>\n

Birlea presented his preliminary findings in June at the annual American Headache Society Scientific Meeting in San Diego. The patients who completed the trial had significant reductions from the baseline period in the number of days with headaches lasting at least four continuous hours. The headaches were less intense and the patients took fewer medications to control them.<\/p>\n

Patients with \u201cpermanent\/continuous\u201d headaches made up half the study group, Birlea noted. Yet even when this especially debilitated group was included, the average number of days with headaches patients described as moderate to severe fell by 16 percent. In patients who had chronic, but not permanent headaches, the drop was nearly 40 percent.<\/p>\n

The number of diagnosed migraine days fell \u201conly\u201d 5 percent for those with permanent headaches, but 41 percent for those who did not have permanent headaches.<\/p>\n

Heading off pain<\/strong><\/p>\n

Stansbury began the trial Jan. 20, completed it and is still using the Cefaly. \u201cIt changed my life,\u201d Stansbury said of the device. \u201cMy life is easier. I have more energy and less pain. It\u2019s been amazing for me.\u201d<\/p>\n

She said she puts the device on every morning, placing the electrode above her eyebrow and running it for 15 to 20 minutes. The stimulation produces a tingling sensation that she found unpleasant at first, but she got used to it. She frequently turns it on for another 10 to 20 minutes shortly after the first treatment.<\/p>\n

The migraines haven\u2019t gone away completely, Stansbury stressed. She self-administers Toradol injections periodically and recently received a Botox injection at UCH, which was prohibited during the trial. But she believes the Cefaly has helped not only to prevent migraines but also decrease their severity.<\/p>\n

\u201cIt nips them in the bud,\u201d she said. She\u2019s even had an occasional headache-free day\u2013 something she hasn\u2019t experienced very often since her birthday seven years ago.<\/p>\n

\u201cI\u2019m dealing with other medical issues, but I feel now that I can control my headaches enough for school and work,\u201d Stansbury said. \u201cI want to make my own money and learn. Every day I am fighting for that.\u201d<\/p>\n

The Cefaly isn\u2019t a cure-all for migraine, Birlea said, but it offers a good option for patients like Stansbury after other therapies fail or even as a first choice.<\/p>\n

\u201cIt is non-invasive, usually well-tolerated and can be used in combination with other treatments,\u201d he said. Patients who are not in the trial can also try the Cefaly device in the Headache Clinic, he added.<\/p>\n

\u201cWhen I see new patients in clinic, I try to offer them everything I know,\u201d Birlea added. \u201cWe want to understand who will benefit the most from this treatment.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

Shauna Stansbury\u2019s 14th birthday party was memorable, but not for the right reasons. The celebration turned sour when Stansbury, now 21, was beset by a headache she compared to \u201csomeone hammering my skull from the inside, a constant pounding.\u201d The pain reduced her to tears, she recalled. The birthday gone bad began a long ordeal […]<\/p>\n","protected":false},"author":2143,"featured_media":3021,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[5],"tags":[204,203,184],"class_list":["post-4685","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovative-care","tag-headache-clinic","tag-migraine-care","tag-neurology"],"acf":[],"yoast_head":"\nTrial aims to help patients zap migraines - UCHealth Today<\/title>\n<meta name=\"description\" content=\"Shauna Stansbury\u2019s 14th birthday party was memorable, but not for the right reasons. 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