{"id":43109,"date":"2021-11-18T13:23:53","date_gmt":"2021-11-18T20:23:53","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=43109"},"modified":"2024-12-24T09:01:53","modified_gmt":"2024-12-24T16:01:53","slug":"how-monoclonal-antibodies-help-people-stay-out-of-the-hospital","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/how-monoclonal-antibodies-help-people-stay-out-of-the-hospital\/","title":{"rendered":"Positive for COVID-19? How monoclonal antibodies help people stay out of the hospital."},"content":{"rendered":"
<\/div>
\"Two
Sandy Overhultz, a nurse at UCHealth Poudre Valley Hospital, cares for Vicky Schommer of Greeley (left), and Lorraine Erdahl of Fort Collins. Monoclonal antibodies help patients who have tested positive for COVID-19 stay out of the hospital. Photo by Kati Blocker, UCHealth.<\/figcaption><\/figure>\n

While vaccination provides excellent protection from COVID-19, if you end up with the coronavirus, monoclonal antibodies can shorten the duration of the disease while cutting the chance of ending up in the hospital by a solid 70%.<\/p>\n

Getting monoclonal antibodies is not quite as easy as taking a pill, and that has presented some challenges. But medical experts have worked to make it easier to get monoclonal antibodies so they can reduce stubbornly high COVID-19 hospitalizations.<\/p>\n

How monoclonal antibodies help<\/strong><\/h2>\n

Monoclonal antibodies are lab-produced proteins that attach to coronavirus-causing SARS-CoV-2 viruses and keep them from invading human cells. The combination of its delivery by infusion and the federal and state involvement in the distribution process has slowed its uptake.

Research and guidelines around monoclonal antibody therapy continue to evolve as new variants of COVID-19 emerge. Please check\u00a0here\u00a0<\/a>for the latest update on monoclonal antibody therapy at UCHealth.<\/div>\n

UCHealth has been leading the monoclonal antibody charge in Colorado, and is taking steps to make it easier to get monoclonal antibodies into the people who need them more quickly and efficiently.<\/p>\n

Speed matters with monoclonal antibodies: they\u2019re ideally administered within three to five days of symptom onset, and the earlier they\u2019re infused, the better they work. To learn more, click here<\/a>.<\/p>\n

Two ways to get monoclonal antibodies<\/strong><\/h2>\n

UCHealth\u2019s Virtual Urgent Care<\/a> is helping quarterback the process in two different ways, says Dr. Adit Ginde<\/a>, a UCHealth emergency physician and vice chair for research in the Department of Emergency Medicine at the University of Colorado School of Medicine. First, those lacking a primary care physician \u2013 or who, for a $49 flat fee, want to move quickly \u2013 can set up a Virtual Urgent Care appointment online<\/a>. Second, for those with primary care physicians, patients can get a referral to Virtual Urgent Care, often avoiding the fee.<\/p>\n

\"Two
Monoclonal antibodies have been proven to help keep patients who have tested positive for COVID-19 out of the hospital. Photo by Kati Blocker, UCHealth.<\/figcaption><\/figure>\n

The cost of infusion is typically covered by insurance. The U.S. government provides the drug at no cost by spending<\/a> $2,100 per dose in an effort to reduce costly hospitalizations and to keep the pandemic in check.<\/p>\n

In either case, Virtual Urgent Care staff versed in monoclonal antibody treatment and scheduling will determine your eligibility for infusion. The criteria are broad: COVID-19 plus any one of the following: being overweight (BMI greater than 25), age 65 or older, pregnant, or immunocompromised\/immunosuppressed; having chronic kidney disease, diabetes, cardiovascular disease, or chronic lung disease. (There\u2019s more \u2013 full list here<\/a>). Virtual Urgent Care will then manage the process on the state website<\/a> and get an appointment scheduled.<\/p>\n

How to get help with monoclonal antibodies<\/strong><\/h2>\n

The aim is to get patients in for monoclonal antibodies and get them in faster. Part of the challenge is to get more providers familiar with the process of prescribing monoclonal antibodies.<\/p>\n

\"Photo
Dr. Adit Ginde<\/figcaption><\/figure>\n

\u201cThis is an \u2018as-soon-as-possible\u2019 treatment,\u201d Ginde said. \u201cIt\u2019s authorized for 10 days after symptom onset, but it\u2019s really most useful within the first few days of illness.\u201d<\/p>\n

Monoclonal antibody infusions are being offered at 130 locations<\/a> around Colorado. That\u2019s in addition to new monoclonal antibody treatment buses<\/a> operating in Pueblo, Colorado Springs, Evans, Grand Junction and Cortez.<\/p>\n

\u2018Everyone benefits\u2019 if monoclonal antibodies are easier to get<\/strong><\/h2>\n

As noted, major clinical trials have shown monoclonal antibodies to reduce the risk of COVID-19 hospitalization by 70% or more. In addition, Ginde says, monoclonal antibodies cut the length of time you feel sick by four full days (Tamiflu, by comparison, shortens influenza-symptom duration by 12 to 24 hours and has little impact on hospitalization numbers).<\/p>\n

In the coming months, antiviral pills may join monoclonal antibody infusions in the health care toolkit. But Merck\u2019s molnupiravir<\/a> isn\u2019t being considered for U.S. Food and Drug Administration emergency use authorization until Nov. 30, and Pfizer has yet to submit data on its promising antiviral Paxlovid<\/a> to the FDA. Until then, monoclonal antibodies are the most effective treatments for keeping COVID-19 infections in check.<\/p>\n

\u201cEveryone benefits, but those most at risk for hospitalization benefit most,\u201d Ginde said. \u201cAnything we can do to keep COVID patients out of the hospital is tremendously important always, and certainly right now. Not only are emergency departments and hospitals operating way above capacity, but the health care workforce is also frayed.<\/p>\n

\"A
Poudre Valley Hospital nurse Sandy Overhultz dons Personal Protective Equipment. Photo by Kati Blocker, UCHealth.<\/figcaption><\/figure>\n

Ginde stressed that monoclonal antibodies are not a \u201cvaccination replacement.\u201d<\/p>\n

Vaccines sharply diminish the risk of catching<\/a> the coronavirus in the first place. But monoclonal antibodies, along with vaccinating as many people as possible, are, he said, \u201ca critical part of our armament to keep the individual safe and keep the health care system and workforce solvent.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

While vaccination provides excellent protection from COVID-19, if you end up with the coronavirus, monoclonal antibodies can shorten the duration of the disease while cutting the chance of ending up in the hospital by a solid 70%. Getting monoclonal antibodies is not quite as easy as taking a pill, and that has presented some challenges. […]<\/p>\n","protected":false},"author":23,"featured_media":43112,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[5],"tags":[4859,4860,9069,162,4781,3981,3405],"class_list":["post-43109","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovative-care","tag-coronavirus","tag-covid-19","tag-covid-19-vaccine","tag-infectious-diseases","tag-research-in-health-care","tag-video-appointment","tag-virtual-health"],"acf":[],"yoast_head":"\nPositive for COVID-19? 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