{"id":33949,"date":"2020-08-27T10:54:37","date_gmt":"2020-08-27T16:54:37","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=33949"},"modified":"2025-01-03T11:02:12","modified_gmt":"2025-01-03T18:02:12","slug":"uchealth-opens-moderna-covid-19-vaccine-trial-with-focus-on-recruiting-minorities","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/uchealth-opens-moderna-covid-19-vaccine-trial-with-focus-on-recruiting-minorities\/","title":{"rendered":"UCHealth opens Moderna COVID-19 vaccine trial with focus on recruiting minorities"},"content":{"rendered":"
<\/div>

Editor’s note: For the most up-to-date COVID-19 vaccine information, please click here<\/a>.<\/strong><\/em><\/p>\n

Michael Rouse saw the news that COVID-19 vaccine trials like the one underway by Moderna were having trouble<\/a> recruiting minorities.<\/p>\n

The Denver retiree recognized the irony and the tragedy of that news. The irony: Black and Hispanic minorities have suffered, per capita, far worse than whites over the course of the pandemic. In Colorado, Black people are twice as likely<\/a> to contract COVID-19 than whites. Blacks who contract the disease here are nearly twice as likely to die than whites who contract it. Colorado Hispanics are three times as likely to contract it as whites, with a mortality rate about 15% higher.<\/p>\n

\":
Michael Rouse was among the first volunteers for UCHealth\u2019s Moderna vaccine trial. Recruiting minorities to participate in COVID-19 trials is essential because disproportionate infection rates for minorities merit extra emphasis, local site\u2019s leader says.\u00a0 Photo by Todd Neff for UCHealth.<\/figcaption><\/figure>\n

The tragedy: a lack of minority representation in coronavirus vaccine trials could well delay the ultimate approval of vaccines \u2013 an approval that will depend on demonstrating vaccine safety and effectiveness across races and ages. Subduing the pandemic will require widespread vaccination. Delaying vaccination could cost thousands of lives.<\/p>\n

At the same time, Rouse, 65, understood why African Americans in particular may be wary of volunteering for a coronavirus vaccine trial: the infamous Tuskegee study<\/a> and the immortal cells of Henrietta Lacks<\/a> are two examples. But Rouse believes that medical ethics are different now.<\/p>\n

\u201cYou have to have faith in our system \u2013 that it\u2019s going to do the right thing,\u201d he said through his surgical mask in the lobby of UCHealth University of Colorado Hospital\u2019s Anschutz Inpatient Pavilion on Aug. 24. \u201cThe results will be beneficial to all of us.\u201d<\/p>\n

Recruiting minorities for COVID-19 vaccine trial<\/strong><\/h3>\n

Rouse filled out a form on the National Institutes of Health website and, when he didn\u2019t hear back, called them. The NIH connected him with Dr. Thomas Campbell<\/a>\u2019s team. Campbell, the University of Colorado School of Medicine virologist and infectious disease specialist leading the Moderna vaccine study at UCH<\/a>, was happy to hear from Rouse.<\/p>\n

\u201cIf we develop a vaccine for COVID-19, we need to make sure it\u2019s safe for African Americans, and the only way to do that is to make sure we have African Americans represented in our vaccine study,\u201d Campbell said.<\/p>\n

\"Dr.
Dr. Thomas Campbell leads the team testing the Moderna coronavirus trial in Colorado at UCHealth University of Colorado Hospital.<\/figcaption><\/figure>\n

University of Colorado is one of 89 hospitals and clinics participating in a national trial that will test the vaccine or placebo on 30,000 volunteers in total. (There will be a 50-50 split in this placebo-controlled, double-blind<\/a> trial.) The first sites started enrolling on July 27; Rouse was among the UCHealth site\u2019s first nine volunteers. They got their first shots on Thursday, Aug. 20. He and the others will receive their booster \u2013 again, either the experimental Moderna vaccine or a placebo \u2013 28 days later.<\/p>\n

UCHealth is ramping up enrollment to a pace of 100 to 125 people a week, and Campbell and his colleagues intend to bring in a more diverse group of volunteers than has been the case with many centers across the country.<\/p>\n

\u201cOur goal is to have between 30% and 40% of our total enrollment from these minority groups,\u201d he said. That\u2019s about what they make up in COVID-19 populations across the state.\u201d<\/p>\n

That\u2019s despite those populations comprising just a quarter of the Colorado\u2019s population.<\/p>\n

To recruit minorities and boost participation in the COVID-19 trial, the team is working a couple of angles. First, they\u2019re reaching out to Black, Hispanic and Native American patients via the UCHealth Epic electronic medical record\u2019s MyHealthConnection. Second, CU School of Medicine and UCHealth infectious-disease specialist Dr. Jose Castillo-Mancilla<\/a> is working with the Mexican and other consulates in Denver as well as community groups.<\/p>\n

\u2018Science is the solution\u2019<\/strong><\/h3>\n

Rouse is an enthusiastic participant in the study, and while the idea of potentially being protected from COVID-19 may be appealing, it isn\u2019t what drove him to participate. First of all, he says, there was a 50% chance he would receive a placebo.<\/p>\n

The prep included a blood draw, a thorough walkthrough of the 22-page contract, and an introduction to the smartphone app with which Rouse was to track possible side effects.<\/p>\n

\"Dr.
Cr. Jose Castillo-Mancilla<\/figcaption><\/figure>\n

While he\u2019s not sure what he received the afternoon of Aug. 20, he did feel some body aches a few hours after the shot. As someone whose thrice-weekly workouts include 50 to 100 chin-ups, he\u2019s well familiar with muscle aches. In fact, he described them as what he sometimes felt like after a heavy workout. A bit of nausea followed, but by the next morning, the body aches and nausea were gone. Minor soreness near the injection site in his shoulder persisted into the weekend.<\/p>\n

Even if he got the actual vaccine, Rouse isn\u2019t taking chances. He and wife Phyllis are both old enough to be at higher risk for coronavirus complications, so they\u2019re continuing to be vigilant about hand-washing, mask-wearing, and avoiding crowded indoor spaces.<\/p>\n

He hopes more minorities join him in the study.<\/p>\n

\u201cI told my family: throughout history, if it were not for people volunteering to do something like this, we wouldn\u2019t have the medications we have now,\u201d Rouse said. \u201cScience is the solution \u2013 not fear.\u201d<\/p>\n

For more information on joining the Moderna COVID-19 trial at UCHealth, email <\/em>thomas.campbell@cuanschutz.edu<\/em>.<\/em><\/p>\n

For information on COVID-19 testing through UCHealth, please click here<\/a>. To find community testing locations throughout Colorado, please click here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Editor’s note: For the most up-to-date COVID-19 vaccine information, please click here. Michael Rouse saw the news that COVID-19 vaccine trials like the one underway by Moderna were having trouble recruiting minorities. The Denver retiree recognized the irony and the tragedy of that news. The irony: Black and Hispanic minorities have suffered, per capita, far […]<\/p>\n","protected":false},"author":23,"featured_media":33952,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[8],"tags":[4859,4860,9069,9038],"class_list":["post-33949","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-coronavirus","tag-covid-19","tag-covid-19-vaccine","tag-vaccines"],"acf":[],"yoast_head":"\nUCH opens Moderna COVID-19 vaccine trial focused on recruiting minorities<\/title>\n<meta name=\"description\" content=\"UCHealth is focued on recruiting minorities for the Moderna COVID-19 vaccine trial. 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