{"id":26410,"date":"2019-09-10T15:00:38","date_gmt":"2019-09-10T21:00:38","guid":{"rendered":"https:\/\/www.uchealth.org\/today\/?p=26410"},"modified":"2022-08-17T14:17:22","modified_gmt":"2022-08-17T20:17:22","slug":"iud-use-cut-rates-of-deadly-ovarian-cancer-around-the-world-new-study-finds","status":"publish","type":"post","link":"https:\/\/www.uchealth.org\/today\/iud-use-cut-rates-of-deadly-ovarian-cancer-around-the-world-new-study-finds\/","title":{"rendered":"IUD use cut rates of deadly ovarian cancer around the world, new study finds"},"content":{"rendered":"
<\/div>
\"young
A new study found that women who used IUDs had significantly lower rates of deadly ovarian cancer. Photo: Getty Images.<\/figcaption><\/figure>\n

A new study of thousands of women around the world found that rates of deadly ovarian cancer declined by up to 32% for women who used contraceptive intrauterine devices or IUDs.<\/p>\n

Led by cancer and family planning doctors at UCHealth University of Colorado Hospital<\/a>, the study marks the first of its kind to bring together the results of multiple international studies and examine how IUDs affected ovarian cancer rates.<\/p>\n

The results, which were released today<\/a>, appear in the October issue of Obstetrics & Gynecology.<\/p>\n

\"Dr.
Dr. Lindsay Wheeler, lead author of a new study on IUDs and ovarian cancer.<\/figcaption><\/figure>\n

\u201cWe know that ovarian cancer is the deadliest of gynecologic cancers. Anything we can do to decrease that risk is very important,\u201d said Dr. Lindsay Wheeler<\/a>, the study\u2019s lead author and a gynecologic oncology fellow at the University of Colorado Cancer Center<\/a> on the Anschutz Medical Campus<\/a>.<\/p>\n

Ovarian cancer accounts for more than 22,000 deaths worldwide each year. In the U.S. alone, the National Cancer Institute<\/a> estimates there will be 22,530 new cases and 13,980 deaths due to ovarian cancer in 2019.<\/p>\n

One of the greatest challenges is that there is no way to screen women for ovarian cancer and symptoms are vague, so women often are diagnosed at an advanced stage.<\/p>\n

Wheeler worked on the study with ovarian cancer specialist, Dr. Saketh Guntupalli<\/a>, and Dr. Stephanie Teal, one of the world\u2019s leading experts on IUDs.<\/p>\n

\u201cThis is a very important study,\u201d said Guntupalli, director of gynecologic oncology at the University of Colorado Cancer Center. \u201cIt\u2019s a meta-analysis, the most powerful of all types of studies we have. It takes data from many different places and pulls all the data together. It\u2019s the first of its kind to look at multiple international sources to see how IUDs affect ovarian cancer.\u201d<\/p>\n

The researchers analyzed results of 11 studies from diverse places including China, Vietnam and Italy and found that IUDs were associated with a significant reduction in the incidence of ovarian cancer. The reductions ranged from 15-to-32%.<\/p>\n

\"Dr.
Dr. Saketh Guntupalli said a new study of IUD use and cancer rates provides critical new information.<\/figcaption><\/figure>\n

The women used many different types of IUDs and the study authors were not able to determine how long the women had used the devices. Nor could they determine exactly why the ovarian cancer rates went down.<\/p>\n

Wheeler and Guntupalli believe either hormones or the immune environment may play a role.<\/p>\n

\u201cMany types of IUDs have hormones in them and exhibit anti-estrogenic effects which may help women who are at high risk for ovarian and uterine cancers<\/a>,\u201d Guntupalli said. \u201cThe second reason was that all the different kinds of IUDs\u2026resulted in some local inflammatory effects. Immune cells increase and are thought to halt the threat of cancer.\u201d<\/p>\n

Back in the 1970s, one brand of IUD was deemed unsafe and pulled off the market. Since then, IUDs have had a strong comeback. Doctors say modern IUDs are extremely safe and effective, with more than a 99% success rate at preventing unwanted pregnancies.<\/p>\n

\u201cWhile not every contraceptive is right for every woman, IUDs are in the top tier of contraceptive methods for their convenience, effectiveness, and health benefits. And, we just found another possible exciting health benefit,\u201d said Teal, the family planning expert. \u201cThis is a significant association, and it is good news for women.\u201d<\/p>\n

In addition to their effectiveness, IUDs are convenient for women because they can work for 7 to 12 years. Women who want to have babies sooner can have them removed any time, Teal said.<\/p>\n

In addition to preventing unwanted pregnancies, Teal said it\u2019s important to understand that IUDs and other contraceptives can have \u201cvery positive effects on women\u2019s health.\u201d<\/p>\n

\"\"
Dr. Stephanie Teal, one of the world’s leading experts on IUDs, said the devices are safe, effective and provide some health benefits beyond preventing unwanted pregnancies.<\/figcaption><\/figure>\n

\u201cContraception can have very profound effects, not just on quality of life, but also potentially on reduction of mortality,\u201d she said.<\/p>\n

Researchers long have known that various birth control methods, including IUDs, reduce the risk of endometrial cancer<\/a>. A similar meta-analysis recently found that the risk of cervical cancer<\/a> went down in women who used IUDS.\u00a0 Previous research has shown that tubal ligation and oral contraceptives decrease ovarian cancer rates. And, doctors routinely use IUDs with hormones to treat women with endometrial cancer.<\/p>\n

But, said Wheeler: \u201cThis study marks the first time researchers also have shown a reduced risk of ovarian cancer with IUDs.\u201d<\/p>\n

The study authors say more research is needed both because they included such a broad array of women who had so many different kinds of IUDs, and because they couldn\u2019t determine if the women had IUDs for \u201c10 years or 10 months,\u201d as Guntupalli said.<\/p>\n

Even with these shortcomings, Guntupalli said the findings are \u201cincredibly compelling\u201d and doctors should consider the effects on cancer along with other non-contraceptive and contraceptive benefits of IUDs.<\/p>\n

\u201cTalk to your physician. Talk to your OBGYN. Determine what the best means of contraception is for you,\u201d Guntupalli said.<\/p>\n

This study, along with additional research, could save women\u2019s lives.<\/p>\n

As the study authors wrote, \u201cThese data suggest a previously unrecognized non-contraceptive benefit of contraceptive IUDs\u2026Given the grave nature of an advanced ovarian cancer diagnosis, even a modest increase in the use of IUDs may lead to a decrease in the incidence of ovarian cancer in a general population of women, leading to a significant population-level effect.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

A new study of thousands of women around the world found that rates of deadly ovarian cancer declined by up to 32% for women who used contraceptive intrauterine devices or IUDs. Led by cancer and family planning doctors at UCHealth University of Colorado Hospital, the study marks the first of its kind to bring together […]<\/p>\n","protected":false},"author":2123,"featured_media":26412,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[8],"tags":[28,9073,4856,351,212],"class_list":["post-26410","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-cancer-care-oncology","tag-gynecologic-cancer-treatment","tag-infertility-and-reproductive-care","tag-primary-care","tag-womens-care"],"acf":[],"yoast_head":"\nIUDs and cancer study: IUDs cut rates of ovarian cancer - 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