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Clinical Trials

Developing the future of medicine

Advances in medicine come from new ideas developed through clinical research.

At University of Colorado Health, we conduct hundreds of clinical trials (also called research trials or research studies) in our ongoing effort to discover and deliver more effective treatment.

As a collaborative medical system, our goal is to translate discoveries made in the laboratory to the patients who will benefit from them, as quickly as possible.

Please review our current available clinical trials below, and call or email the contact person(s) listed for a trial to get a more thorough explanation of that study.

  • Note that this is not an exhaustive list of all of our open clinical trials – we may be conducting other studies not yet in our database. Call a contact person for that type of study to learn more.
  • If you are a patient or referring physician, please note that not all patients will be eligible for all trials. Please either make an appointment to see one of our expert physicians or contact a faculty member directly.


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Use Each of the Column Titles Below to Filter Clinical Trials

Cancer Trials

collapse Cancer Focus : All Cancers ‎(5)
Phase I Safety Pharmacokinetic and Pharmacodynamic study of PF-02341066 a C-Met/HGFR selective Tyrosine Kinase inhibitor administered orally to patients with advanced cancer.All Cancers
NRG-BR001 A Phase I Study of Stereotactic Body Radiotherapy (SBRT) for the Treatment of Multiple MetastasesAll Cancers
PT-112-101 A Phase I, Open-Label, Dose-Escalation Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-122 Injection in Subjects with Advanced Solid TumorsAll Cancers
08-02 A Phase I, Dose-Escalation Study of the Safety, Pharmacokinetics and Efficacy of Weekly Intravenous Briciclib in Patients with Advanced Solid TumorsAll Cancers
AG120-C-002 A Phase I, Multicenter, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects with Advanced Solid Tumors, Including Glioma, with an IDH1 MutationAll Cancers
collapse Cancer Focus : Bladder Cancer/Urothelial Cancer ‎(2)
S1314 A Randomized Phase II Study of CO-eXpression ExtrapolatioN (COXEN) with Neoadjuvant Chemotherapy for Localized, Muscle-Invasive Bladder Cancer (version date 7/26/13)Bladder Cancer/Urothelial Cancer
S1011: A Phase III Surgical Trial to Evaluate the Benefit of a Standard Versus an Extended Pelvic Lymphadenectomy Performed At Time of Radial Cystectomy For Muscle Invasive Urothelial Cancer.Bladder Cancer/Urothelial Cancer
collapse Cancer Focus : Blood Diseases (Except Leukemia) ‎(4)
University of Colorado Cancer Center: Hematological Malignancies Tissue BankBlood Diseases (Except Leukemia)
GSK 115523: A phase III, randomised, observer-blind, placebo-controlled, multicentre, clinical trial to assess the prophylactic efficacy, safety, and immunogenicity of GSK Biologicals' herpes zoster gE/AS01B candidate vaccine when administered intramBlood Diseases (Except Leukemia)
CMX001-333 A Prospective Observational Study for the Long-Term Follow-up of Subjects Previously Enrolled in Selected Clinical Studies of CMX001 (The Chimerix CMX001 Registry)Blood Diseases (Except Leukemia)
GO29365 A Phase IB/II Study Evaluating the Safety, Tolerability and Anti-Tumor Activity of Polatuzumab Vedotin (DCDS4501A) in Combination with Rituximab (R) or Obinutuzumab (G) Plus Bendamustine (B) in Relapsed or Refractory Follicular or Diffuse Large B-Blood Diseases (Except Leukemia)
collapse Cancer Focus : Brain and Nervous System Tumors ‎(3)
A Phase III Clinical Trial Evaluating DCVax«-L, Autologous Dendritic Cells Pulsed with Tumor Lysate Antigen for the Treatment of Glioblastoma Multiforme.Brain and Nervous System Tumors
RTOG 1205 Randomized Phase II Trial of Concurrent Bevacizumab and Re-Irradiation versus Bevacizumab Alone as Treatment for Recurrent GlioblastomaBrain and Nervous System Tumors
NRG-BN001 Randomized Phase II Trial of Hypofractionated Dose-Escalated Photon IMRT or Proton Beam Therapy Versus Conventional Photon Irradiation with Concomitant and Adjuvant Temozolomide in Patients with Newly Diagnosed GlioblastomaBrain and Nervous System Tumors
collapse Cancer Focus : Breast Cancer ‎(17)
Helping Ourselves, Helping Others: The Young Women's Breast Cancer StudyBreast Cancer
A Translational Study of the Interactions between Prior Pregnancy and the Biologic Subtype of Breast Cancer in Defining the Cancer: Host Immunologic InteractionBreast Cancer
I-SPY2: Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2Breast Cancer
SWOG S1007: A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less.Breast Cancer
Phase 0 Study of Normal Postpartum Involution to Identify the Feasibility of a Life Window for Breast Cancer ChemopreventionBreast Cancer
SWOG S1207: Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/neu Negative Breast Cancer.Breast Cancer
RTOG 1304/NSABP B-51/Endorsed Study: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy who ConvBreast Cancer
A011202 A Randomized Phase III Trial Evaluating the Role of Axillary Lymph Node Dissection in Breast Cancer Patients (cT1-3 N1) who have Positive Sentinel Lymph Node Disease After Neoadjuvant ChemotherapyBreast Cancer
ONT-380-005 A Phase 1b, Open-Label Study to Assess the Safety and Tolerability of ONT-380 Combined with Capecitabine and Trastuzumab, Alone and in Combination in HER2+ Metastatic Breast CancerBreast Cancer
ONT-10-104 A Phase 1b Study of ONT-10 and Varlilumab in Patients with Advanced Ovarian Cancer or Breast CancerBreast Cancer
C31001 A Phase 1b/2 Study of Safety and Efficacy of MLN0128 (Dual TORC1/2 Inhibitor) in Combination with Exemestane or Fulvestrant Therapy in Postmenopausal Women with ER+/HER2- Advanced or Metastatic Breast Cancer that has Progressed on Treatment with EvBreast Cancer
9785-CL-1121 A Phase 2, Multicenter, Open-Label Study to Assess the Efficacy and Safety of Enzalutamide with Trastuzumab in Subjects with HER2+ AR+ Metastatic or Locally Advanced Breast Cancer Breast Cancer
WO29479 A Multistage, Phase II Study Evaluating the Safety and Efficacy of Cobimetinib in Combination with Paclitaxel as First-Line Treatment for Patients with Metastatic Triple-Negative Breast CancerBreast Cancer
NSABP B-55/BIG 6-13 A Randomised, Double-Blind, Parallel Group, Placebo-controlled Multi-Centre Phase III Study to Assess the Efficacy and Safety of Olaparib Versus Placebo as Adjuvant Treatment in Patients with Germline BRCA I/2 Mutations and High Risk HBreast Cancer
I3Y-MC-JPBO A Phase 2 Study of Abemaciclib in Patients with Brain Metastases Secondary to Hormone Receptor Positive Breast CancerBreast Cancer
NRG-BR002 A Phase IIR/III Trial of Standard of Care Therapy with or without Stereotactic Body Radiotherapy (SBRT) and/or Surgical Ablation for Newly Oligometastatic Breast CancerBreast Cancer
MM-302-02-02-03 A Randomized, Multicenter, Open Label Study of MM-302 Plus Trastuzumab vs Chemotherapy, of Physician's Choice, Plus Trastuzumab in Anthracycline Na´ve Patients with Locally Advanced/Metastatic HER2-Positive Breast CancerBreast Cancer
collapse Cancer Focus : Digestive System Cancer ‎(9)
CALGB C80702, A Phase III Trial of 6 Versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon CancerDigestive System Cancer
BAY 73-4506/15982: A randomized, double blind, placebo-controlled, multicenter phase III study of regorafenib in patients with hepatocellular carcinoma (HCC) after sorafenibDigestive System Cancer
CTEP LOI# 9231 - A phase I trial of dinaciclib (SCH727965) and MK-2206 in metastatic pancreatic cancer with an expansion cohort in advanced pancreatic cancerDigestive System Cancer
54F28-004 A Phase 1b Dose Escalation Study of OMP-54F28 in Combination with Sorafenib in Patients with Hepatocellular CancerDigestive System Cancer
HALO-109-202: A Phase 2, Randomized, Multicenter Study of PEGPH20 (PEGylated Recombinant Human Hyaluronidase) Combined with nab-Paclitaxel Plus Gemcitabine Compared With nab-Paclitaxel Plus Gemcitabine in Subjects With Stage IV Previously Untreated PancreDigestive System Cancer
RTOG 1112 Randomized Phase III Study of Sorafenib Versus Stereotactic Body Radiation Therapy Followed by Sorafenib in Hepatocellular CarcinomaDigestive System Cancer
S1406 Randomized Phase II Study of Irinotecan and Cetuximab with or without Vemurafenib in BRAF Mutant Metastatic Colorectal CancerDigestive System Cancer
N1048 A Phase II/III Trial of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation Versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total MesorectaDigestive System Cancer
D081FC00001 A Phase III, Randomised, Double-Blind, Placebo-Controlled, Multicentre Study of Maintenance Olaparib Monotherapy in Patients with gBRCA Mutated Metastatic Pancreatic Cancer Whose Disease has not Progressed on First Line Platinum Based ChemotheDigestive System Cancer
collapse Cancer Focus : Endocrine Cancer ‎(2)
D1532C00065: A Randomised, Double Blind Study to Compare the Complete Remission Rate Following a 5-Week Course of Selumetinib or Placebo and Single Dose Adjuvant Radioactive Iodine Therapy in Patients with Differentiated Thyroid Cancer Endocrine Cancer
Alliance A091305 A Phase 2 Randomized Study of Efatutazone, an Oral PPAR Agonist, in combination with Paclitaxel Versus Paclitaxel in Patients with Advanced Anaplastic Thyroid CancerEndocrine Cancer
collapse Cancer Focus : Female Reproductive Cancer ‎(10)
GOG 0213 Phase III randomized controled clinical trial of carboplatin and paclitaxel alone or in combination with bevacizumab followed by bevacizumab and secondary cytoreductive surgery in platinum sensitive recurent ovarian peritoneal primary and fallopiFemale Reproductive Cancer
Prospective Evaluation of Vaginal Stenosis and Sexual Function in Patients with Pelvic Malignancies Treated with Multimodality Therapy Including Radiation Therapy versus Surgery AloneFemale Reproductive Cancer
GOG 0274: A Phase III Trial of Adjuvant Chemotherapy Following Chemoradiation as Primary Treatment for Locally Advanced Cervical Cancer Compared To Chemoraditiaon Alone: The Outback Trial ( ANZGOG 0902)Female Reproductive Cancer
GOG 0225: Can Diet and Physical Activity Modulate Ovarian and Primary Peritoneal Cancer Progression-Free Survival?Female Reproductive Cancer
ARRAY-162-311: The MILO Study (MEK Inhibitor in Low-grade Serous Ovarian Cancer): A Multinational, Randomized, Open-label Phase 3 Study of MEK162 vs. Physician's Choice Chemotherapy in Patients with Recurrent or Persistent Low-grade Serous CarcinomasFemale Reproductive Cancer
RTOG 1203 - A Randomized Phase III Study Of Standard Vs. IMRT Pelvic Radiation For Post-Operative Treatment Of Endometrial And Cervical Cancer (TIME-C)--RTOG CCOP StudyFemale Reproductive Cancer
GOG-0277 A Phase III Randomized Trial of Gemcitabine (NSC #613327) Plus Docetaxel (NSC# 628503) Followed By Doxorubicin (NSC# 123127 versus Observation for Uterus-Limited High-Grade Uterine LeiomyosarcomaFemale Reproductive Cancer
GOG 0286B A Randomized Phase II/III Study of Paclitaxel/Carboplatin/Metformin (NSC#91485) Versus Paclitaxel/Carboplatin/Placebo as Initial Therapy for Measurable Stage III or IVA, Stage IVB, or Recurrent Endometrial CancerFemale Reproductive Cancer
NRG-CC002 Pre-Operative Assessment and Post-Operative Outcomes of Elderly Women with Gynecologic Cancers Female Reproductive Cancer
collapse Cancer Focus : Head and Neck Cancers ‎(4)
Head and Neck Squamous cell cancer tissue collection for animal xenograft studiesHead and Neck Cancers
RTOG 1216 Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered with Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and NeckHead and Neck Cancers
MK-3475-040-00 A Phase III Randomized Trial of MK-3475 (Pembrolizumab) versus Standard Treatment in Subjects with Recurrent or Metastatic Head and Neck CancerHead and Neck Cancers
collapse Cancer Focus : Kidney Cancer ‎(2)
SWOG S0931: EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, A Phase III Study Kidney Cancer
An international Phase 3 Randomized Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (ADAPT)Kidney Cancer
collapse Cancer Focus : Leukemia/Myelodysplasia ‎(5)
SWOG S0919: A Phase II Study of Idarubicin and Ara-C in Combination with Pravastatin for Relapsed Acute Myelogenous LeukemiaLeukemia/Myelodysplasia
Celgene RV-AML-PI - 0759: Sequential Treatment with Azacitidine and Lenalidomide for Relapsed and Refractory Patients with Acute Myeloid LeukemiaLeukemia/Myelodysplasia
A Phase 2 Study of PF-04449913 for the Treatment of Acute Leukemia Patients with High Risk of Post-Allogeneic Stem Cell Transplantation RelapseLeukemia/Myelodysplasia
Multi-center, open-label randomized study of single or double myeloablative cord blood transplantation with or without infusion of off-the-shelf ex vivo expanded cryopreserved cord blood progenitor cells in patients with hematologic malignancies (2603.00)Leukemia/Myelodysplasia
M14-358 A Phase 1b Study of ABT-199 (GDC-0199) in Combination with Azacitidine or Decitabine in Treatment Naive Subjects with Acute Myelogenous Leukemia Who Are Greater Than or Equal to 65 Years of Age and Who Are Not Eligible for Standard Induction TheraLeukemia/Myelodysplasia
collapse Cancer Focus : Lung Cancer ‎(24)
SPORE 24: Biomarkers and dysplastic respiratory epithelium (version B).Lung Cancer
Lung Cancer Tissue Bank ProtocolLung Cancer
CALGB C140503: A Phase III Randomized Trial of Lobectomy versus sublobar Resection for Small (< 2 cm) peripheral non-small cell lung cancerLung Cancer
RTOG 0538 Phase III comparison of thoracic radiotherapy regimens in patients with limited small cell lung cancer also receiving cisplatin and etoposideLung Cancer
Lung Cancer Mutation Consortium ProtocolLung Cancer
Pulmonary Nodule Biomarker Trial Lung Cancer
BRF113928: A Phase II study of the selective BRAF kinase inhibitor GSK2118436 in subjects with advanced non-small cell lung cancer and BRAF mutationsLung Cancer
A phase II study of ponatinib in cohorts of patients with lung cancer preselected using different candidate predictive biomarkersLung Cancer
2012-0618: A Randomized Phase II Study Assessing the Efficacy of Local Consolidative Therapy for Non-small Cell Lung Cancer patients with Induced Oligometastatic DiseaseLung Cancer
D1532C00079:A Phase III, Double-Blind, Randomised, Placebo-Controlled Study to Assess the Efficacy and Safety of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Combination with Docetaxel, in Patients Receiving Second-Line Treatment for KRAS Mutation-Lung Cancer
Pulmonary Nodule Biomarker Trial Lung Cancer
E-3810-II-02 A Single Arm, Open-Label, Phase II Study to Assess the Efficacy of the Dual VEGFR-FGFR Tyrosine Kinase Inhibitor, Lucitanib, Given Orally as a Single Agent to Patients with FGFR1-Driven Lung CancerLung Cancer
BO28984 Randomized, Multicenter, Phase III, Open-Label Study of Alectinib versus Crizotinib in Treatment-Naive Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung CancerLung Cancer
LOXO-TRK-14001 A Phase 1a/1b Study of the Oral TRK Inhibitor LOXO-101 in Subjects with Adult Solid TumorsLung Cancer
RTOG 1306 A Randomized Phase II Study of Individualized Combined Modality Therapy for Stage III Non-Small Cell Lung Cancer (NSCLC)Lung Cancer
S1300 A Randomized, Phase II Trial of Crizotinib Plus Pemetrexed Versus Pemetrexed Monotherapy in ALK-Positive Non-Squamous NSCLC Patients Who Have Progressed Systemically After Previous Clinical Benefit from Crizotinib MonotherapyLung Cancer
S1400 Phase II/III Biomarker-Driven Master Protocol For Second Line Therapy of Squamous Cell Lung Cancer (Screening Step)Lung Cancer
A081105 Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)Lung Cancer
A151216 Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)Lung Cancer
CO-1686-022 TIGER 1: A Randomized, Open-Label, Phase II Study of CO-1686 or Erlotinib as First-Line Treatment of Patients with EGFR-Mutant Advanced Non-Small Cell Lung Cancer (NSCLC)Lung Cancer
E4512 A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib Versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion ProteinLung Cancer
M14-361 A Phase I Dose Escalation and Phase 2 Randomized Double-Blind Study of Veliparib in Combination with Carboplatin and Etoposide as a Therapy of Treatment-Naive Extensive Stage Disease Small Cell Lung CancerLung Cancer
NRG-LU001 Randomized Phase II Trial of Concurrent Chemoradiotherapy +/- Metformin HCL in Locally Advanced NSCLCLung Cancer
RXDX-101-01 A Phase I/2A, Multicenter, Open-Label Study of Oral RXDX-101 in Adult Patients with Locally Advanced or Metastatic Cancer Confirmed to be Positive for TRKA, TRKB, TRKC, ROS1, or ALK Molecular AlterationsLung Cancer
collapse Cancer Focus : Melanoma (Except Eye) ‎(4)
CLDE225A2112: A Phase Ib, a multi-center, two parallel group, open-label, drug-drug, interaction study to assess the effect of LDE225 on the pharmacokinetics of bupropion and warfarin in patients with advanced solid tumors.Melanoma (Except Eye)
S1320: A Randomized, Phase II Trial of Intermittent Versus Continuous Dosing of Dabrafenib (NSC-763760) and Trametinib (NSC-763093) in BRAF V600E/K Mutant MelanomaMelanoma (Except Eye)
S1221: Phase I/II study of the Safety and Efficacy of the AKT inhibitor GSK 2141795 in Combination with the BRAF inhibitor Dabrafenib in Patients with BRAF Mutant CancerMelanoma (Except Eye)
CL-CA-P01-00-US (Ver07-31-13) Phase III, Randomized, Double-Blind, Multicenter Trial of Autologous Dendritic Cells Loaded with Irradiated Autologous Tumor Cells in GM-CSF (DC-TC) vs Autologous Peripheral Blood Mononuclear Cells in GM-CSF (MC) for the TreaMelanoma (Except Eye)
collapse Cancer Focus : Multiple Myeloma/Plasma Cell Tumors ‎(1)
collapse Cancer Focus : No Cancer ‎(1)
A Randomized Phase II Chemoprevention Study of Pioglitazone Versus Placebo in Patients at High Risk for Lung CancerNo Cancer
collapse Cancer Focus : Prostate Cancer ‎(11)
CALGB C90203: Randomized phase III study of neo-adjuvant Docetaxel and Androgen deprivation prior to radical prostatectomy vs immediate radical prostatectomy in patients with high risk clinically localized prostate cancer.Prostate Cancer
BNIT-PRV-301. A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F ▒ GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic, Castrate-Resistant Prostate Cancer.Prostate Cancer
RTOG 0924 - Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized TrialProstate Cancer
Phase II open label study of the effect of GTx-758 as secondary hormonal therapy on serum PSA and serum free testosterone levels in men with metastatic castration resistant prostate cancer maintained on androgen deprivation therapyProstate Cancer
A Pilot Study to Enhance F18 FDG-PET Imaging of Prostate Cancers with the Metabolic Inhibitor Ranolazine Prostate Cancer
S1216: A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 With Androgen Deprivation Therapy + Bicalutamide in Patients With Newly Diagnosed Metastatic Hormone Sensitive Prostate CancerProstate Cancer
Phase I/II Study of Abiraterone Acetate and Prednisone in Combination with Cabazitaxel in Patients with Metastatic Castrate Resistant prostate Cancer that is Refractory to DocetaxelProstate Cancer
SP005 A Randomized, Double-Blind, Multicenter, Parallel-Group Phase III Study to Evaluate Efficacy and Safety of DCVAC/PCa versus Placebo in Men with Metastatic Castration Resistant Prostate Cancer Eligible for 1st Line ChemotherapyProstate Cancer
CU004 PROspective Study of the IMPACT of Decipher Prostate Cancer Classifier on Physician and Patient Treatment Consideration and Decisions Following Radical Prostatectomy [PRO-IMPACT]Prostate Cancer
A031201 Phase III Trial of Enzalutamide (NSC #766085) Versus Enzalutamide, Abiraterone and Prednisone for Castration Resistant Metastatic Prostate CancerProstate Cancer
collapse Cancer Focus : Sarcoma ‎(2)
Multi-center, Open-Label, Single-Arm Study of Yondelis (trabectedin) for Subjects With Locally Advanced or Metastic Soft Tissue Sarcoma Who Have Relapsed or Are Refractory to Standard of Care Treatment. Phase III ET743-SAR-3002Sarcoma
A091202 A Phase II, Randomized, Double Blinded Study of the Peroxisome Proliferator-Activated Receptor Gamma Agonist, Efatutazone vs Placebo in Patients with Previsouly Treated, Unresectable Myxoid LiposarcomaSarcoma
collapse Cancer Focus : Skin Cancer (Except Melanoma) ‎(1)
ML28296.RegiSONIC: A prospective observational study of treatment patterns and effectiveness and safety outcomes in advanced basal cell carcinoma and basal cell carcinoma nevus syndrome patientsSkin Cancer (Except Melanoma)
Other Trial Focus
Levothyroxine for Chronic Hives in Patients with Thyroid Disease Allergies, Skin (Dermatology)
INSITE Investigation of Sacroiliac Fusion TreatmentBack, Neck, and Spine, Bones, Joints, and Muscles
A Prospective, Multi-Center, Randomized Study Comparing the VertiFlex® Superion™ Interspinous Spacer (ISS) to the X-STOP® Interspinous Process Decompression (IPD®) device in healthy adults suffering from at least 6 months of moderate spinal stenosis symptBack, Neck, and Spine
Efficacy of Low Dose Intravenous Heparin in Preventing Thromboembolism in the SICUBlood Disorders/Diseases, Drugs (Pharmacology), Heart & Circulation
Role of Vascular Function: Oxygen Delivery v. Oxygen Utilization in Exercise Impairment in Type 2 DiabetesBones, Joints, and Muscles, Diabetes, Exercise, Heart & Circulation
COX Inhibition & Musculoskeletal Responses to Exercise (MOXI)Bones, Joints, and Muscles, Drugs (Pharmacology)
Effects of Calcium Supplementation on Changes in Bone Mineral Density in Competitive Male and Female Road CyclistsBones, Joints, and Muscles
Overweight adolescents needed for brain imaging research studyBrain & Nervous System, Weight & Metabolism
Exploratory study of different doses of endurance exercise in people with Parkinson’s diseaseBrain & Nervous System, Exercise
A pilot phase II trial of Hypofractionated Intensity-modulated Radiotherapy (H-IMRT) combined with Temozolomide and Bavacizumab in patients with newly diagnosed GBMBrain & Nervous System
A Randomized Placebo-Controlled Trial Exploring the Efficacy of Oral Arginine to Improve Cellular Immune Function in Patients with Glioblastoma MultiformeBrain & Nervous System
A randomized, double-blinded, placebo-controlled, multicenter phase II study to evaluate the efficacy and safety of onartuzumab in combination with bevacizumab relative to placebo + bevacizumab in patients with glioblastoma at first recurrence.Brain & Nervous System
Effects of Serum Fatty Acid Lowering on Insulin Sensitivity, Cardiovascular Function, and Exercise Capacity in Non-insulin Dependent DiabetesDiabetes, Drugs (Pharmacology), Exercise
EXSCEL (EXenatide Study of Cardiovascular Event Lowering Trial): A Randomized, Placebo-controlled Clinical Trial to Evaluate Cardiovascular Outcomes After Treatment with Exenatide Once Weekly in Patients with Type 2 Diabetes MellitusDiabetes, Drugs (Pharmacology), Heart & Circulation
The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness StudyDiabetes, Endocrine (Hormones)
Iron reduction by phlebotomy for the prevention and treatment of type 2 diabetesDiabetes, Endocrine (Hormones)
A Phase III, Multinational, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Investigate the Clinical Efficacy and Safety of DiaPep277® in Newly Diagnosed Type 1 Diabetes SubjectsDiabetes, Drugs (Pharmacology)
Novo Nordisk NN1218-3853 - FIAsp: Efficacy and Safety of FIAsp Compared to Insulin Aspart in Combination with Insulin Glargine and Metformin in Adults with Type 2 DiabetesDiabetes
Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Mutli-Center Study to Evaluate the Efficacy and Safety of Once-Daily Administration of a Chemokine CCR2/5 Receptor Antagonist (PF-04634817) in Adults with Type 2 Diabetes and Overt NepDiabetes, Endocrine (Hormones)
Mediators of Perceived Exercise Effort in Type 2 Diabetes – Barriers to Physical ActivityDiabetes, Exercise, Heart & Circulation
SUSTAIN trial seeks individuals with type 2 diabetes and heart diseaseDiabetes, Endocrine (Hormones), Heart & Circulation
The ENDO Research Study for Type 2 DiabetesDiabetes, Endocrine (Hormones), Weight & Metabolism
Adipose tissue research studyDiabetes, Drugs (Pharmacology), Endocrine (Hormones)
Effects of PPAR Ligands on Ectopic Fat Accumulation and InflammationDiabetes, Drugs (Pharmacology), Endocrine (Hormones)
Fat Oxidation in Obese and Reduced Obese HumansDigestive, Weight & Metabolism
Improving the Care of Post-Extubation Dysphagia (PED) in Survivors of Critical IllnessDigestive, Ear, Nose, and Throat (includes hearing loss), Intensive Care/Critical Care, Lungs & Respiratory
Persons with active, moderate to severe ulcerative colitis needed (MERIT-UC)Digestive
Dexmedetomidine vs. Midazolam for Facilitating Extubation in Critically Ill Medical and Surgical ICU Patients: A Randomized, Double-Blind StudyDrugs (Pharmacology), Intensive Care/Critical Care, Lungs & Respiratory
Phase III Study on the Efficacy of Glutamine Dipeptide-Supplemented Parenteral Nutrition in Surgical ICU PatientsDrugs (Pharmacology), Infections, Intensive Care/Critical Care
Role of Vascular Function: Oxygen Delivery v. Oxygen Utilization in the Exercise Impairment in Type 2 DiabetesDiabetes, Heart & Circulation, Weight & Metabolism
An Open-Label Expanded Access Trial of Plant Cell Expressed Recombinant Human Glucocerebrosidase (Prgcd) in Patients With Gaucher's Disease Who Require Enzyme Replacement Therapy (Protalix)Genetics/Hereditary Conditions
Fibroblasts and Mononuclear Fibrogenic Cells Drive Right Ventricular Pulmonary Arterial Uncoupling in Pulmonary Arterial HypertensionHeart & Circulation, Lungs & Respiratory
Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial (Cabana)Heart & Circulation
Circulating Cells, Plasma, and Serum Markers in Peripheral Blood and Their Role in Pulmonary HypertensionHeart & Circulation, Lungs & Respiratory
Collaborative Care to Alleviate Symptoms and Adjust to Illness (CASA)Heart & Circulation
Measuring strain and strain rate in the right ventricle by speckle tracking echocardiography in patients with pulmonary arterial hypertension: Correlation with invasive and clinical parameters.Heart & Circulation, Lungs & Respiratory
Mulimodal Image Integration for the Planning and Guidance of Structural Heart Disease InterventionsHeart & Circulation
SYMPHONY studyHeart & Circulation, Lungs & Respiratory
TAPIT-1: Treatment of Pulmonary Hypertension Associated COPD with Inhaled Treprostinil-1Heart & Circulation, Lungs & Respiratory
The PARTNER II Trial: Placement of AoRTicTraNscathetER Valves Trial The Safety and Effectiveness of the SAPIEN XT™ Transcatheter Heart Valve with NovaFlex and Ascendra 2 delivery systems (Transfemoral and Transapical) in Intermediate Risk for Aortic ValveHeart & Circulation
The Vest Prevention of Early Sudden Death Trial (VEST) and Predicition of ICD Therapies Study (Predicts)Heart & Circulation
Rxercise: Mediators of Perceived Exercise Effort in Type 2 Diabetes – Barriers to Physical ActivityWeight & Metabolism
Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)Heart & Circulation
Real World Expanded Multicenter Study of the MitraClip System (REALISM)Heart & Circulation
Ovarian Tissue Freezing For Fertility Preservation In Females Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen: A Study By The National Physicians Cooperative Of The Oncofertility ConsortiumReproductive medicine
A Randomized Trial of Fetal ECG ST Segment and T Wave Analysis as an Adjunct to Electronic Fetal Heart Rate Monitoring (STAN)Pregnancy, Childbirth, and Newborn Care
A Randomized Trial To Prevent Congenital Cytomegalovirus (CMV)Pregnancy, Childbirth, and Newborn Care
AMBITION StudyLungs & Respiratory
An Observational Study of Hepatitis C Virus in PregnancyPregnancy, Childbirth, and Newborn Care
Antenatal Late Preterm Steroids (ALPS) Ancillary Study: Genetic Variation, Response to Antenatal Steroids, and Late Preterm Morbidity
CoPARC: To develop new interventions for individuals with alcohol abuse and dependence that will decrease their predisposition for pneumoniaLungs & Respiratory
Antenatal Late Preterm Steroids (ALPS): Randomized Placebo-Controlled Trial
Inhaled Nitric Oxide/INO Pulse DS Combination ProductLungs & Respiratory
National Biological Sample and Data Repository for Pulmonary Arterial HypertensionLungs & Respiratory
Oral Remodulin: A Phase III, International, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Event Driven Study to Compare the Time to First Clinical Worsening in Subjects with Pulmonary Arterial Hypertension Receiving UT-15C in Combination witLungs & Respiratory
Riociguat in Chronic Thromboembolic Pulmonary Hypertension (CTEPH)Lungs & Respiratory
Study of Rituxan in PAHLungs & Respiratory
Prospective Cohort of Ulcerative Colitis and Crohn’s Disease Patients Undergoing Surgery to Identify Risk Factors for Post-Operative InfectionDigestive
Crohn's Disease - a Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Multiregional, One Year Study to Assess the Efficacy and Safety of Twice Daily Oral Rifaximin Delayed Release Tablets for Induction of Clinical Remission . . .Digestive, Immune Disorders
Healthy Postmenopausal Women Needed for Cardiovascular Research StudyEndocrine (Hormones), Heart & Circulation, Women's Health
Healthy Women Needed for Cardiovascular Research StudyEndocrine (Hormones), Heart & Circulation, Women's Health
Looking for Healthy Women to Participate in a Research Study on Females, Aging, Metabolism, and Exercise (FAME)Endocrine (Hormones), Women's Health
Investigations in Gestational Origins of Lifetime Development: Understanding How Health Begins Before BirthEndocrine (Hormones), Pregnancy, Childbirth, and Newborn Care, Women's Health
RISE IIP: A randomized, double-blind, phase II study to investigate the efficacy and safety of riociguat (0.5, 1.0, 1.5, 2.0 and 2.5 mg TID) in patients with symptomatic pulmonary hypertension associated with idiopathic interstitial pneumonia (IIP)Heart & Circulation, Lungs & Respiratory
Impact of Sitagliptin on Cardiovascular Exercise Performance in Type 2 DiabetesDiabetes, Heart & Circulation
Healthy Men and Women Between 60 and 85 Years OldExercise
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